8-Methoxymethyl-3-isobutyl-1-methylxanthine
8-Methoxymethyl-3-isobutyl-1-methylxanthine (CAS: 78033-08-6), a xanthine derivative with the molecular formula C12H18N4O3 and a molecular weight of 266.30 g/mol, is a valuable research chemical. It functions primarily as an inhibitor in biological research, particularly concerning cyclic nucleotide metabolism and phosphodiesterase activity. Its applications are centered within biochemical studies and cell biology, aiding in the investigation of cellular signaling pathways.
- IUPAC
- 8-Methoxymethyl-IBMX
- Synonyms
- 8-Methoxymethyl-IBMX

Phosphodiesterase Inhibition
This compound serves as a selective inhibitor of phosphodiesterase enzymes, crucial for studying cyclic nucleotide signaling pathways in various biological systems.
Cellular Signaling Research
Utilised in cell biology to investigate the roles of cyclic AMP (cAMP) and cyclic GMP (cGMP) in cellular processes and signal transduction.
Neuroscience Studies
Applied in neuroscience research to explore the function of phosphodiesterases in neuronal signalling and related physiological processes.
Biochemical Assays
A reagent used in biochemical assays to understand enzyme kinetics and mechanisms, specifically related to phosphodiesterase activity.
| Molecular weight | 266.30 |
|---|---|
| Empirical formula | C12H18N4O3 |
| Assay | ≥98% |
| Solubility | ethanol: soluble10 mg/mL |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... PDE1A(5136), PDE1B(5153) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 8-Methoxymethyl-3-isobutyl-1-methylxanthine used for?
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8-Methoxymethyl-3-isobutyl-1-methylxanthine is primarily used as a research chemical, acting as a phosphodiesterase inhibitor in studies of cyclic nucleotide metabolism, cell signalling, and neuroscience.
What is the CAS number and chemical formula?
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The CAS number for 8-Methoxymethyl-3-isobutyl-1-methylxanthine is 78033-08-6, and its chemical formula is C12H18N4O3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 8-Methoxymethyl-3-isobutyl-1-methylxanthine with an assay of ≥98%. TSS does not represent this product as USP, BP, EP, or any pharmacopoeial grade.
What are the safety and handling precautions for this chemical?
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Handling requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. This compound is classified with a WGK Germany of 3, indicating a high hazard level.
How is this product shipped and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, handling international shipments with appropriate documentation and care.
How can I request a sample or quote for 8-Methoxymethyl-3-isobutyl-1-methylxanthine?
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To request a sample or a quote, please contact our sales department through the provided channels on our website, specifying the product name and CAS number.
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