8-Chloroadenosine-3′,5′-cyclic monophosphorothioate, Rp-isomer
8-Chloroadenosine-3′,5′-cyclic monophosphorothioate, Rp-isomer (CAS 142754-27-6) is a thio-substituted cyclic adenosine monophosphate analog. This compound is a stable, membrane-permeable analogue of cyclic AMP (cAMP), often employed as a tool in biochemical and cell biology research. It serves as an effective inhibitor of various cyclic nucleotide-dependent enzymes and phosphodiesterases, making it valuable for studying cellular signalling pathways.
- IUPAC
- Rp-8-Cl-cAMPS
- Synonyms
- 142754-27-6Rp-8-Cl-cAMPS
Biochemical Research
Used as a research tool to investigate cyclic nucleotide metabolism and signaling pathways. Its stability and membrane permeability allow for effective intracellular studies.
Enzyme Inhibition Studies
Acts as an inhibitor for cyclic nucleotide-dependent enzymes and phosphodiesterases, aiding in the characterization and understanding of their functions in biological systems.
Cell Signaling Investigations
Facilitates research into cell signaling cascades, particularly those involving cyclic AMP (cAMP), by modulating intracellular signaling events.
| Empirical formula | C10H10ClN5O5PSNa |
|---|---|
| Assay | ≥99% (HPLC) |
| Form | solid |
| Storage temperature | −20°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Packaging | vial of 5 μmol |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 8-Chloroadenosine-3′,5′-cyclic monophosphorothioate, Rp-isomer used for?
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This compound is primarily used as a research tool in biochemical and cell biology studies, particularly for investigating cyclic nucleotide metabolism, enzyme inhibition, and cell signaling pathways.
What are the CAS number and formula for 8-Chloroadenosine-3′,5′-cyclic monophosphorothioate, Rp-isomer?
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The CAS number is 142754-27-6. The empirical formula is C10H10ClN5O5PSNa.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound with an assay of ≥99% (HPLC). We do not represent it as USP, BP, EP, or other pharmacopoeia grades unless explicitly stated in the product data.
What are the safety considerations for handling this chemical?
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When handling, ensure adequate personal protective equipment including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter. This compound has a WGK rating of 3 in Germany, indicating it is hazardous.
How is 8-Chloroadenosine-3′,5′-cyclic monophosphorothioate, Rp-isomer packaged and shipped?
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The product is supplied in a vial containing 5 μmol and is stored at -20°C. TSS exports fine chemicals globally.
How can I request a quote or sample?
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Please contact our sales team or use the online form on our website to request a quote or sample for 8-Chloroadenosine-3′,5′-cyclic monophosphorothioate, Rp-isomer.
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