8-Amino-1-octanethiol hydrochloride
8-Amino-1-octanethiol hydrochloride (CAS: 937706-44-0) is a versatile bifunctional molecule with the empirical formula C8H19NS · HCl and a molecular weight of 197.77 g/mol. This compound features both an amine and a thiol group, making it suitable for a range of applications in materials science, particularly for surface modification and the creation of self-assembled monolayers (SAMs) on gold surfaces.
- IUPAC
- 8-Mercaptooctylamine hydrochloride
- Synonyms
- 8-Mercaptooctylamine hydrochloride

Self-Assembled Monolayers (SAMs)
Utilised in the formation of SAMs, this thiol derivative can anchor to gold surfaces via its thiol group. The terminal amine group can then be further modified to immobilise biomolecules or other functional materials, enabling applications in biosensing.
Biosensor Development
The molecule's ability to functionalise surfaces, particularly for immobilising proteins, is crucial for developing biosensors. It aids in achieving high levels of protein immobilisation and suppressing non-specific adsorption, thereby improving sensor performance.
Surface Functionalisation
The amino group can be readily reacted with amine-reactive compounds, allowing for the tailored functionalisation of surfaces. This is valuable in micro and nanoelectronics for precise surface engineering.
| Molecular weight | 197.77 |
|---|---|
| Empirical formula | C8H19NS · HCl |
| Assay | 95% |
| Storage temperature | 2-8°C |
| Application | Self Assembly Molecules (SAMs); the amino group is usually modified using amine-reactive materials; such as proteins or biomaterials; to functionalize the gold surface. It is used for biosenors with large amounts of immobilized protein and suppression of nonspecific adsorption |
| Melting point | 158-163 °C |

Hazard statements
- H410Very toxic to aquatic life with long-lasting effects
Precautionary statements
- P273Avoid release to the environment
- P501Dispose of contents and container per local regulations
| Transport (UN / ADR) | UN 3077 9 / PGIII |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | N |
| Risk statements (R) | 50/53 |
| Safety statements (S) | 60-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 8-Amino-1-octanethiol hydrochloride used for?
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8-Amino-1-octanethiol hydrochloride is primarily used for creating self-assembled monolayers (SAMs) on gold surfaces, with applications in biosensing and general surface functionalisation via its terminal amine group.
What is the CAS number and formula for 8-Amino-1-octanethiol hydrochloride?
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The CAS number is 937706-44-0 and the empirical formula is C8H19NS · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 8-Amino-1-octanethiol hydrochloride with an assay of 95%. This product is intended for research and development purposes and is not supplied as USP, BP, EP, or any other pharmacopoeia grade.
How should 8-Amino-1-octanethiol hydrochloride be handled and stored?
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This compound is classified as harmful to aquatic life with long-lasting effects (H410). It should be handled with appropriate personal protective equipment and stored at 2-8°C to maintain its stability.
Is 8-Amino-1-octanethiol hydrochloride a controlled substance?
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The provided data does not indicate that 8-Amino-1-octanethiol hydrochloride is a controlled substance.
How is 8-Amino-1-octanethiol hydrochloride shipped?
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As per the ADR information, it is shipped as UN 3077, Class 9, Packing Group III, indicating it is an environmentally hazardous substance, solid, n.o.s.
How can I request a sample or quote for 8-Amino-1-octanethiol hydrochloride?
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Please contact our sales team directly via the website or phone to request a sample or a quotation for 8-Amino-1-octanethiol hydrochloride.
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