(8α,9S)-6′-Methoxycinchonan-9-amine trihydrochloride
(8α,9S)-6′-Methoxycinchonan-9-amine trihydrochloride (CAS: 1231763-32-8) is a chiral amine derived from Cinchona alkaloids. This compound serves as a valuable reagent and catalyst in asymmetric synthesis, facilitating the stereoselective construction of complex organic molecules. Its utility is particularly noted in applications requiring chiral induction, making it an important tool for chemists engaged in the synthesis of enantiomerically pure compounds for pharmaceutical and materials science research.
- IUPAC
- (8S,9S)-9-Amino-9-deoxyepiquinine trihydrochloride,(S)-(6-Methoxyquinolin-4-yl)((2S,4S,5R)-5-vinylquinuclidin-2-yl)methanamine trihydrochloride
- Synonyms
- (8α,9S)-6′-Methoxycinchonan-9-amine trihydrochloride
Asymmetric Catalysis
This Cinchona alkaloid derivative functions as a chiral catalyst or ligand in asymmetric synthesis. It can promote stereoselective reactions, leading to the formation of enantiomerically enriched products, which is critical in pharmaceutical development.
Chiral Ligand Synthesis
The compound can be employed in the synthesis of more complex chiral ligands. These tailored ligands are essential for a wide range of enantioselective transformations in organometallic chemistry and catalysis.
Reagent in Organic Synthesis
As a structurally defined chiral amine, it acts as a specialised reagent for specific synthetic transformations where stereochemical control is paramount. Its unique structural features allow for precise molecular interactions.
| Empirical formula | C20H25N3O · 3HCl |
|---|---|
| Assay | ≥90%≥90.0% (HPLC)90.0-110.0% (AT) |
| Optical activity | [α]/D +65.0±2.0°, c = 1 in 0.1 M HCl |
Hazard statements
- H301Toxic if swallowed
Precautionary statements
- P301IF SWALLOWED
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25 |
| Safety statements (S) | 45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (8α,9S)-6′-Methoxycinchonan-9-amine trihydrochloride used for?
+
This compound is primarily used in asymmetric synthesis as a chiral catalyst, ligand, or reagent to promote stereoselective reactions and produce enantiomerically enriched compounds.
What is the CAS number and formula for (8α,9S)-6′-Methoxycinchonan-9-amine trihydrochloride?
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The CAS number is 1231763-32-8, and the empirical formula is C20H25N3O · 3HCl.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies this product with an assay of ≥90% (HPLC) and 90.0-110.0% (AT). This is a research grade material and is not represented as USP, BP, EP, or other pharmacopoeial grades.
What are the safety concerns associated with this chemical?
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This compound is classified as acutely toxic (Danger, H301) and is harmful if swallowed. Appropriate personal protective equipment and handling procedures must be followed, and it should only be handled by trained personnel in a well-ventilated area. Accidental exposure requires immediate medical attention (P301 + P310).
How is (8α,9S)-6′-Methoxycinchonan-9-amine trihydrochloride packaged and exported?
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This chemical is handled and packaged according to stringent international shipping regulations for hazardous materials. It is exported globally by Tech Serve Solutions, adhering to all relevant transport classifications, including UN 2811, Class 6.1, Packing Group III.
How can I request a sample or quote for this product?
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To request a sample or a detailed quotation, please contact our sales team via the website or direct email, providing your specific requirements and shipping details.
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