7-Hydroxy-5-methyl[1,2,4]triazolo[1,5-a]pyrimidine
7-Hydroxy-5-methyl[1,2,4]triazolo[1,5-a]pyrimidine (CAS: 2503-56-2) is a heterocyclic organic compound with the molecular formula C6H6N4O and a molecular weight of 150.14 g/mol. This chemical serves as a versatile building block and reactant in organic synthesis. Its applications include the preparation of Ruthenium(II)-Hmtpo complexes, dihydroorotate dehydrogenase inhibitors with antimalarial activity, and it is utilized in Vilsmeier reactions of conjugated systems.
- IUPAC
- 5-Methyl[1,2,4]triazolo[1,5-a]pyrimidin-7-ol,6-Methyl-4-hydroxy-1,3,3a,7-tetraazaindene,7-Hydroxy-5-methyl-1,3,4-triazaindolizine,NSC 32071,NSC 511493
- Synonyms
- 5-a]pyrimidine,2503-56-2, C6H6N4O, 5-Methyl[1,2,4]triazolo[1,5-a]pyrimidin-7-ol,6-Methyl-4-hydroxy-1,3,3a,7-tetraazaindene,7-Hydroxy-5-methyl-1,3,4-triazaindolizine,NSC 32071,NSC 511493
![7-Hydroxy-5-methyl[1,2,4]triazolo[1,5-a]pyrimidine (C6H6N4O) — chemical structure, CAS 2503-56-2; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F2503-56-2.png&w=3840&q=75)
Synthesis of Ruthenium(II)-Hmtpo Complexes
This compound acts as a reactant in the synthesis of specific Ruthenium(II)-Hmtpo complexes, contributing to the development of novel coordination compounds.
Development of Antimalarial Agents
It is employed as a reactant in the synthesis of dihydroorotate dehydrogenase inhibitors, which are being investigated for their potential antimalarial activity.
Vilsmeier Reactions
7-Hydroxy-5-methyl[1,2,4]triazolo[1,5-a]pyrimidine is a reactant in Vilsmeier reactions involving conjugated carbocycles and heterocycles, facilitating carbon-carbon bond formation.
Pharmacological Investigations
The compound is used in research investigating its pharmacological activity, particularly its potential binding to HIV TAR RNA.
Study of Silver Bromide Microcrystals
It serves as an additive in studies aimed at understanding the space charge layer within silver bromide microcrystals.
| Molecular weight | 150.14 |
|---|---|
| Empirical formula | C6H6N4O |
| Assay | 98% |
| Application | Reactant for the synthesis of: • Ruthenium(II)-Hmtpo complexes1• Dihydroorotate dehydrogenase inhibitors with antimalarial activity2Reactant for the Vilsmeier reaction of conjugated carbocycles and heterocycles3Investigations of the pharmacological activity caused by binding to HIV TAR RNA4Additive to study the space charge layer in silver bromide microcrystals5 |
| Melting point | 280-283 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 7-Hydroxy-5-methyl[1,2,4]triazolo[1,5-a]pyrimidine used for?
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7-Hydroxy-5-methyl[1,2,4]triazolo[1,5-a]pyrimidine is used as a reactant for the synthesis of Ruthenium(II)-Hmtpo complexes, dihydroorotate dehydrogenase inhibitors with antimalarial activity, and in Vilsmeier reactions. It is also investigated for its pharmacological activity and used as an additive in the study of silver bromide microcrystals.
What is the CAS number and formula for 7-Hydroxy-5-methyl[1,2,4]triazolo[1,5-a]pyrimidine?
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The CAS number is 2503-56-2 and the empirical formula (Hill notation) is C6H6N4O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical with an assay of 98%. We do not represent this product as USP, BP, EP, or other pharmacopoeial grades unless explicitly stated in the product documentation.
How should 7-Hydroxy-5-methyl[1,2,4]triazolo[1,5-a]pyrimidine be handled?
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This compound is classified as a Warning. It may cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves, should be used. Ensure good ventilation.
Is 7-Hydroxy-5-methyl[1,2,4]triazolo[1,5-a]pyrimidine exported by TSS?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 7-Hydroxy-5-methyl[1,2,4]triazolo[1,5-a]pyrimidine.
How can I request a sample or quote for this chemical?
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To request a sample or a quotation, please contact our sales team through the website or by phone. Please reference the product name and CAS number (2503-56-2).
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