6-Nitrophthalide
6-Nitrophthalide (CAS: 610-93-5), with the molecular formula C8H5NO4 and a molecular weight of 179.13 g/mol, is a valuable organic building block. This compound functions as a lactone and a carbonyl compound, frequently employed in chemical synthesis. Its known applications include the preparation of derivatives such as 3-bromo-6-nitrophthalide and its subsequent reductive methylation to form 6-dimethylaminophthalide. Tech Serve Solutions supplies this chemical for research and development purposes.

Synthesis of Brominated Derivatives
6-Nitrophthalide serves as a precursor in the synthesis of halogenated compounds. It has been utilised for the preparation of 3-bromo-6-nitrophthalide, offering a route to further functionalised molecules.
Preparation of Aminophthalides
Through reductive methylation, 6-Nitrophthalide can be transformed into 6-dimethylaminophthalide. This reaction highlights its utility in generating amino-substituted lactone structures.
Organic Synthesis Intermediate
As a functionalised phthalide derivative, 6-Nitrophthalide acts as a versatile intermediate in various organic synthesis pathways. Its structure allows for diverse chemical modifications.
| Molecular weight | 179.13 |
|---|---|
| Empirical formula | C8H5NO4 |
| Assay | 95% |
| Application | 6-Nitrophthalide has been used in the preparation of 3-bromo-6-nitrophthalide1. It undergoes reductive methylation to form 6-dimethylaminophthalide2. |
| Melting point | 140-145 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 6-Nitrophthalide used for?
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6-Nitrophthalide is used as an intermediate in organic synthesis, notably in the preparation of derivatives such as 3-bromo-6-nitrophthalide and 6-dimethylaminophthalide.
What is the CAS number and formula for 6-Nitrophthalide?
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The CAS number for 6-Nitrophthalide is 610-93-5, and its molecular formula is C8H5NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 6-Nitrophthalide with an assay of 95%. This product is supplied for research and development purposes and is not represented as USP, BP, or EP grade.
What are the safety and handling precautions for 6-Nitrophthalide?
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When handling 6-Nitrophthalide, it is essential to use appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used. The substance is classified under WGK 3 in Germany, indicating a significant hazard to water.
How can I request a sample or quote for 6-Nitrophthalide?
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To request a sample or a quote for 6-Nitrophthalide, please contact our sales department through the website or by phone.
Does Tech Serve Solutions export 6-Nitrophthalide?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 6-Nitrophthalide.
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