6β-Hydroxytestosterone
6β-Hydroxytestosterone (CAS: 62-99-7, C19H28O3) is a white to off-white solid with a molecular weight of 304.42 g/mol. This compound is primarily utilised in biochemical research, particularly for assays investigating cytochrome P450 enzyme activity. It serves as a useful substrate or standard in studies related to drug metabolism and cellular signaling pathways. TSS supplies 6β-Hydroxytestosterone with a purity of ≥97% (HPLC).
- IUPAC
- 4-Androstene-6β,17β-diol-3-one,6β, 17β,-Dihydroxyandrost-4-en-3-one
Cytochrome P450 Activity Assays
6β-Hydroxytestosterone has been employed in studies utilising rat hepatocytes to assess Cytochrome P450 (CYP) enzyme activity. It serves as a substrate in these assays to quantify enzyme kinetics and inhibition.
Drug Metabolism Research
This compound has been used in studies focused on CYP3A4 substrate selection. Understanding its interaction with CYP enzymes aids in predicting drug metabolism pathways and potential drug-drug interactions.
Cellular Signaling Investigations
As a bioactive small molecule, 6β-Hydroxytestosterone may be used in research exploring cellular signaling cascades, particularly those involving steroid hormone pathways.
| Molecular weight | 304.42 |
|---|---|
| Empirical formula | C19H28O3 |
| Assay | ≥97% (HPLC) |
| Colour | white to off-white |
| Solubility | acetonitrile: solubleethanol: solublemethanol: soluble |
| Storage temperature | 2-8°C |
| Application | 6β-Hydroxytestosterone has been used for CYP3A activity assays in rat hepatocytes1 and has also been used for CYP3A4 substrate selection studies2. |
| Melting point | ≥205 °C |
Hazard statements
- H351Suspected of causing cancer
- H360May damage fertility or the unborn child
Precautionary statements
- P201Obtain special instructions before use
- P281Use personal protective equipment as required
- P308IF exposed or concerned
| Protective equipment | Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 61-40 |
| Safety statements (S) | 22-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 6β-Hydroxytestosterone used for?
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6β-Hydroxytestosterone is used in biochemical research, primarily for Cytochrome P450 activity assays in systems like rat hepatocytes and for CYP3A4 substrate selection studies.
What is the CAS number and molecular formula for 6β-Hydroxytestosterone?
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The CAS number for 6β-Hydroxytestosterone is 62-99-7, and its molecular formula is C19H28O3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 6β-Hydroxytestosterone with a minimum purity of 97% as determined by HPLC. It is supplied as a research-grade chemical and is not represented as USP, BP, or EP grade.
How should 6β-Hydroxytestosterone be handled?
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Handling requires caution due to potential health hazards. It is classified with Danger signal word, associated with H351 (Suspected of causing cancer) and H360 (May damage fertility or the unborn child). Appropriate personal protective equipment including eyeshields, gloves, and respiratory protection (e.g., N100 respirator) is essential. Always consult the Safety Data Sheet before handling.
Is 6β-Hydroxytestosterone a controlled substance?
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The provided data indicates hazard classifications T (Toxic) with European risk statements R61 (May cause harm to the unborn child) and R40 (Limited evidence of carcinogenic effects). Further details on controlled substance status may be available upon request.
How is 6β-Hydroxytestosterone packed and shipped?
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6β-Hydroxytestosterone is stored at 2-8°C. TSS, as a specialist global supplier and exporter, ensures appropriate packaging and shipping methods are used for this chemical, adhering to all relevant regulations.
How can I request a sample or quote for 6β-Hydroxytestosterone?
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Please contact our sales team through the website or direct email to request a sample or a quotation for 6β-Hydroxytestosterone.
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