6-Fluoroindole
6-Fluoroindole (CAS: 399-51-9, C8H6FN, MW: 135.14) is a fluorinated heterocyclic building block supplied by Tech Serve Solutions. It serves as a key reactant in the synthesis of various biologically active compounds, including potential anticancer immunomodulators, antibacterial and antifungal agents, and inhibitors for conditions like diabetes and HIV. This compound is essential for researchers exploring novel therapeutic avenues in medicinal chemistry.
- IUPAC
- NSC 520436

Anticancer Immunomodulator Precursors
Used as a reactant in the preparation of tryptophan dioxygenase inhibitors, specifically pyridyl-ethenyl-indoles, which are investigated for their potential as anticancer immunomodulators.
Antibacterial and Antifungal Agents
Serves as a crucial building block in the synthetic pathways for developing novel antibacterial and antifungal agents, contributing to the discovery of new antimicrobials.
Diabetes Management Therapeutics
A reactant in the synthesis of Sodium-Dependent Glucose Co-transporter 2 (SGLT2) Inhibitors, compounds studied for the management of hyperglycemia in diabetes.
Serotonin Reuptake Inhibitor Development
Employed in the synthesis of potent and selective serotonin reuptake inhibitors (SSRIs), agents relevant to neurological and psychiatric research.
HIV-1 Attachment Inhibitor Synthesis
Acts as a reactant in the preparation of molecules designed to inhibit HIV-1 attachment, contributing to the development of new antiviral strategies.
| Molecular weight | 135.14 |
|---|---|
| Empirical formula | C8H6FN |
| Assay | 98% |
| Application | • Reactant for preparation of tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles as potential anticancer immunomodulators1• Reactant for preparation of antibacterial agents2• Reactant for preparation of antifungal agents3• Reactant for preparation of Sodium-Dependent Glucose Co-transporter 2 (SGLT2) Inhibitors for the Management of Hyperglycemia in Diabetes4• Reactant for preparation of Potent Selective Serotonin Reuptake Inhibitors5,6• Reactant for preparation of Inhibitors of HIV-1 attachment7 |
| Melting point | 72-76 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 6-Fluoroindole used for?
+
6-Fluoroindole is used as a reactant in the synthesis of various biologically active compounds, including potential anticancer immunomodulators, antibacterial and antifungal agents, Sodium-Dependent Glucose Co-transporter 2 (SGLT2) Inhibitors for diabetes management, potent selective Serotonin Reuptake Inhibitors, and Inhibitors of HIV-1 attachment.
What are the CAS number and chemical formula for 6-Fluoroindole?
+
The CAS number for 6-Fluoroindole is 399-51-9, and its chemical formula is C8H6FN.
What grade and purity does Tech Serve Solutions supply for 6-Fluoroindole?
+
Tech Serve Solutions supplies 6-Fluoroindole with an assay of 98%. This product is not intended for USP, BP, EP, or other pharmacopoeia applications unless explicitly stated, and TSS does not represent it as such.
How should 6-Fluoroindole be handled safely?
+
6-Fluoroindole is a Warning substance classified with H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Appropriate personal protective equipment includes a dust mask type N95, eyeshields, and gloves. Ensure good ventilation and avoid breathing dust.
Is 6-Fluoroindole available for export or international shipping?
+
Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals and can fulfil international orders for 6-Fluoroindole.
How can I request a quote or sample of 6-Fluoroindole?
+
To request a quote or sample of 6-Fluoroindole, please contact our sales team through the website or by direct inquiry, providing your specific requirements.
▶ Related products

1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis

1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis