6-Chloronicotinoyl chloride
6-Chloronicotinoyl chloride (CAS: 66608-11-5, Formula: C6H3Cl2NO) is a heterocyclic organic compound with a molecular weight of 176.00 g/mol. This reactive acyl chloride serves as a key intermediate and building block in organic synthesis, particularly for the introduction of the 6-chloronicotinoyl moiety into various molecular structures. Its utility is primarily in research and development for the creation of novel chemical entities.

Organic Synthesis Intermediate
6-Chloronicotinoyl chloride is employed as a versatile reagent in the synthesis of complex organic molecules. It facilitates acylation reactions, enabling the formation of amide and ester linkages crucial for building larger structures.
Pharmaceutical Research
This compound acts as a precursor in the development of potential pharmaceutical agents. Its structure allows for derivatization, contributing to the exploration of new drug candidates with specific biological activities.
Agrochemical Development
The 6-chloropyridine core present in this molecule makes it a valuable starting material for the synthesis of novel agrochemicals. Researchers utilise it to investigate new pesticides and herbicides.
Material Science
As a functionalised heterocyclic compound, 6-Chloronicotinoyl chloride can be incorporated into polymers or used in the synthesis of specialised materials with unique electronic or physical properties.
| Molecular weight | 176.00 |
|---|---|
| Empirical formula | C6H3Cl2NO |
| Assay | 97% |
| Melting point | 48-51 °C(lit.) |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Flash point | 110 °C / 230 °F |
| Transport (UN / ADR) | UN 3261 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 6-Chloronicotinoyl chloride used for?
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6-Chloronicotinoyl chloride is primarily used as a building block and intermediate in organic synthesis, particularly for the preparation of pharmaceuticals, agrochemicals, and novel materials.
What is the CAS number and formula for 6-Chloronicotinoyl chloride?
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The CAS number is 66608-11-5, and the empirical formula is C6H3Cl2NO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 6-Chloronicotinoyl chloride with an assay of 97%. This product is intended for laboratory and research use; we do not represent it as USP, BP, EP, or pharmaceutical grade.
How should 6-Chloronicotinoyl chloride be handled safely?
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6-Chloronicotinoyl chloride is a corrosive substance (Danger, H314) that causes severe skin burns and eye damage. Appropriate personal protective equipment, including eyeshields, face shields, gloves, and respiratory protection (N100 or P3 filters), is essential. Handle only in a well-ventilated area or fume hood.
How is 6-Chloronicotinoyl chloride packed, shipped, and exported?
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This chemical is typically packed in UN-approved containers suitable for corrosive materials (UN 3261, Class 8, PG II). TSS offers reliable global shipping and export services for laboratory reagents and fine chemicals.
How can I request a sample or quote for 6-Chloronicotinoyl chloride?
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To request a sample or a quote, please contact our sales department via the website or email, providing your required quantity and shipping details.
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