5-(Trifluoromethyl)-3-((trimethylsilyl)ethynyl)pyridin-2-amine
5-(Trifluoromethyl)-3-((trimethylsilyl)ethynyl)pyridin-2-amine (CAS: 1036027-52-7) is a specialised organic compound with the molecular formula C11H13F3N2Si and a molecular weight of 258.32 g/mol. This fluorinated pyridine derivative, featuring a silyl-protected alkyne, serves as a valuable building block in complex organic synthesis. Its structure makes it particularly useful in the development of novel pharmaceutical intermediates and advanced materials.

Pharmaceutical Intermediate Synthesis
This compound acts as a key intermediate in the synthesis of diverse pharmaceutical candidates. The trifluoromethyl and silylethynyl pyridine motifs offer unique reactivity for drug discovery programmes.
Heterocyclic Building Block
As a functionalised pyridine, it is employed in the construction of more complex heterocyclic systems. Its specific substitution pattern allows for targeted derivatisation in medicinal chemistry research.
Materials Science
The unique electronic properties conferred by the trifluoromethyl group and the ethynyl moiety can be exploited in the development of functional materials and organic electronics.
Chemical Research Reagent
It is used in academic and industrial research laboratories for exploring novel synthetic methodologies and developing new chemical entities.
| Molecular weight | 258.32 |
|---|---|
| Empirical formula | C11H13F3N2Si |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-(Trifluoromethyl)-3-((trimethylsilyl)ethynyl)pyridin-2-amine used for?
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This compound is primarily used as a building block in organic synthesis, particularly for developing pharmaceutical intermediates and novel heterocyclic compounds. It also finds applications in materials science research.
What is the CAS number and formula for this chemical?
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The CAS number is 1036027-52-7 and the molecular formula is C11H13F3N2Si.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical as a research-grade product. The specific assay is typically greater than 95%, but please contact us for batch-specific details. TSS does not represent this product as USP, BP, EP, or pharmaceutical grade.
What are the safety and handling considerations for this compound?
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While specific hazards for this compound are not detailed in the provided data, general precautions for handling fine chemicals should be observed. This includes working in a well-ventilated area, avoiding contact with skin and eyes, and using appropriate personal protective equipment. Always consult the Safety Data Sheet (SDS) for comprehensive handling and hazard information.
How is this chemical typically packed, shipped, and exported?
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Tech Serve Solutions packs chemicals in accordance with international shipping regulations for hazardous and non-hazardous materials. We export globally, ensuring compliance with all relevant customs and transport laws.
How can I request a sample or a quote for this chemical?
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To request a sample or a quote, please visit the product page on our website and use the 'Request a Quote' or 'Sample Request' form, or contact our sales team directly via email or phone.
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