5-Methyl-2-(tributylstannyl)pyridine
5-Methyl-2-(tributylstannyl)pyridine (CAS: 189195-41-3, Formula: C18H33NSn) is an organotin compound with a molecular weight of 382.17 g/mol. It is primarily utilised as a reagent in Stille cross-coupling reactions, a vital tool in organic synthesis for forming carbon-carbon bonds. Supplied by Tech Serve Solutions with an assay of 95%, this compound is essential for advanced chemical research and development.
- IUPAC
- Tributyl-(5-methylpyridin-2-yl)stannane
- Synonyms
- Tributyl-(5-methylpyridin-2-yl)stannane
Stille Cross-Coupling Reactions
5-Methyl-2-(tributylstannyl)pyridine serves as a key organostannane reagent in Stille coupling. This palladium-catalysed reaction efficiently constructs new carbon-carbon bonds by coupling organotin compounds with organic halides or pseudohalides.
Organic Synthesis Intermediate
This pyridine derivative functions as a versatile building block in complex organic synthesis. Its specific structure allows for the introduction of the 5-methylpyridin-2-yl moiety into various organic frameworks, facilitating the creation of novel molecular architectures.
Research and Development
Utilised in academic and industrial research laboratories, 5-Methyl-2-(tributylstannyl)pyridine aids in the exploration of new synthetic methodologies and the development of target molecules, particularly in medicinal chemistry and materials science.
| Molecular weight | 382.17 |
|---|---|
| Empirical formula | C18H33NSn |
| Assay | 95% |
| Density | 1.106 g/mL at 25 °C |
| Refractive index | n20/D 1.514 |
| Storage temperature | 2-8°C |
| Application | Used in Stille cross coupling reactions. |
Hazard statements
- H301Toxic if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H372Causes damage to organs through prolonged exposure
- H410Very toxic to aquatic life with long-lasting effects
Precautionary statements
- P273Avoid release to the environment
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P305IF IN EYES
- P314Get medical attention if you feel unwell
- P501Dispose of contents and container per local regulations
| Flash point | >110 °C / >230 °F |
|---|---|
| Transport (UN / ADR) | UN 2788 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T,N |
| Risk statements (R) | 21-25-36/38-48/23/25-50/53 |
| Safety statements (S) | 36/37/39-45-60-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Methyl-2-(tributylstannyl)pyridine used for?
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5-Methyl-2-(tributylstannyl)pyridine is used as a reagent in Stille cross-coupling reactions and as an intermediate in organic synthesis for introducing the 5-methylpyridin-2-yl group.
What are the CAS number and formula for 5-Methyl-2-(tributylstannyl)pyridine?
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The CAS number is 189195-41-3, and the empirical formula (Hill notation) is C18H33NSn.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 5-Methyl-2-(tributylstannyl)pyridine with an assay of 95%. This product is not represented as USP, BP, EP, or any other pharmacopoeia grade.
What are the primary hazards associated with 5-Methyl-2-(tributylstannyl)pyridine?
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This compound is classified as toxic if swallowed, toxic in contact with skin, and causes skin and serious eye irritation. It may also cause damage to organs through prolonged or repeated exposure and is very toxic to aquatic life with long-lasting effects. Handle with appropriate personal protective equipment in a well-ventilated area.
How is 5-Methyl-2-(tributylstannyl)pyridine packed, shipped, and exported?
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5-Methyl-2-(tributylstannyl)pyridine is packed and shipped according to international regulations for hazardous materials, adhering to UN 2788, Class 6.1, Packing Group III. TSS exports globally, complying with all relevant shipping and customs requirements.
How can I request a quote or sample of 5-Methyl-2-(tributylstannyl)pyridine?
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To request a quote or a sample, please visit the Tech Serve Solutions website or contact our sales department directly with your inquiry, referencing the product name and CAS number.
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