5-Ethoxycarbonyl-2-thienylzinc bromide solution
5-Ethoxycarbonyl-2-thienylzinc bromide solution (CAS: 352530-37-1; Formula: C7H7BrO2SZn; MW: 300.49 g/mol) is a valuable organozinc reagent. Supplied as a 0.5 M solution in THF, this compound finds application in organic synthesis, particularly for introducing thienyl moieties into complex molecules. Its reactivity profile makes it a key intermediate for the preparation of advanced materials and pharmaceuticals.
Cross-Coupling Reactions
This organozinc bromide serves as a nucleophilic coupling partner in palladium-catalyzed cross-coupling reactions, such as Negishi couplings. It facilitates the formation of carbon-carbon bonds with aryl and heteroaryl halides.
Synthesis of Thiophene Derivatives
It is utilized in the construction of functionalised thiophene rings, which are prevalent structural motifs in pharmaceuticals, organic electronics, and agrochemicals.
Organometallic Chemistry
As an organozinc halide, it belongs to a class of reagents essential for various synthetic transformations, offering controlled reactivity and functional group tolerance.
| Molecular weight | 300.49 |
|---|---|
| Empirical formula | C7H7BrO2SZn |
| Density | 0.994 g/mL at 25 °C |
| Concentration | 0.5 M in THF |
| Storage temperature | 2-8°C |
Hazard statements
- H225Highly flammable liquid and vapour
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H351Suspected of causing cancer
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P281Use personal protective equipment as required
- P305IF IN EYES
| Flash point | -17 °C / 1.4 °F |
|---|---|
| Transport (UN / ADR) | UN 2056 3 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xn |
| Risk statements (R) | 11-19-36/37-40 |
| Safety statements (S) | 16-26-36/37 |
| Supplemental hazards | May form explosive peroxides. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Ethoxycarbonyl-2-thienylzinc bromide solution used for?
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This reagent is primarily used in organic synthesis, particularly for palladium-catalyzed cross-coupling reactions and the construction of functionalised thiophene derivatives.
What is the CAS number and chemical formula?
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The CAS number is 352530-37-1 and the chemical formula is C7H7BrO2SZn.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product as a 0.5 M solution in THF. We do not claim USP, BP, or EP grade unless explicitly stated in the product specifications.
How should this chemical be handled safely?
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This is a highly flammable liquid and vapour (H225). It causes serious eye irritation (H319) and may cause respiratory irritation (H335). There is suspicion it may cause cancer (H351). It may also form explosive peroxides. Handle with appropriate personal protective equipment in a well-ventilated area, away from ignition sources. Store at 2-8°C.
Is this product controlled or scheduled?
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Based on the provided data, this product is not indicated as a controlled or scheduled substance.
How is this product packed, shipped, and exported?
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This product is classified under UN 2056, Packing Group II, indicating it is shipped as a flammable liquid. Tech Serve Solutions is experienced in global export of chemicals.
How can I request a sample or quote?
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Please contact our sales team via the website or email to request a sample or a formal quotation for 5-Ethoxycarbonyl-2-thienylzinc bromide solution.
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