5-(Dimethylamino)-1-naphthalenesulfonamide
5-(Dimethylamino)-1-naphthalenesulfonamide (CAS: 1431-39-6) is a chemical compound with a molecular weight of 250.32 g/mol. It is primarily utilised for its fluorescent properties, making it valuable in various detection and labelling applications. This sulfonamide derivative is often employed as a fluorescent probe or label in biochemical research and chemical synthesis due to its emission characteristics.
- IUPAC
- DNSA,Dansyl amide
- Synonyms
- DNSA, Dansyl amide

Fluorescent Labelling and Probes
This compound serves as a fluorescent label or probe, emitting light at specific wavelengths (λex 280 nm; λem 470 nm when bound to carbon anhydrase, or λem 580 nm in ethanol). Its properties make it suitable for detecting and visualising biological molecules and processes in research settings.
Biochemical Research
Utilised in biochemical studies, the compound can interact with proteins such as carbon anhydrase, exhibiting distinct fluorescence emission spectra upon binding. This allows for the study of protein-ligand interactions and enzyme activity.
Chemical Synthesis
As an organic building block, 5-(Dimethylamino)-1-naphthalenesulfonamide can be incorporated into more complex molecular structures. Its functional groups allow for further chemical modifications and the creation of novel compounds for various research purposes.
Detection Applications
The fluorescent nature of this sulfonamide enables its use in analytical and detection methods. It can be employed in assays where fluorescence is a key indicator for the presence or concentration of a target analyte.
| Molecular weight | 250.32 |
|---|---|
| Linear formula | (CH3)2NC10H6SO2NH2 |
| Assay | 99% |
| Grade | for fluorescence |
| Melting point | 218-221 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Fluorescence | λex 280 nm; λem 470 nm (bound to carbon anhydrase)λem 580 in ethanol |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-(Dimethylamino)-1-naphthalenesulfonamide used for?
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5-(Dimethylamino)-1-naphthalenesulfonamide (CAS: 1431-39-6) is used as a fluorescent label, fluorescent probe, in biochemical research, chemical synthesis, and other detection applications due to its specific fluorescence properties.
What is the CAS number and formula for 5-(Dimethylamino)-1-naphthalenesulfonamide?
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The CAS number is 1431-39-6 and the linear formula is (CH₃)₂NC₁₀H₆SO₂NH₂.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 5-(Dimethylamino)-1-naphthalenesulfonamide with an assay of 99% and a grade for fluorescence. We do not represent this product as USP, BP, EP, or other pharmacopoeia grades.
What are the safety and handling precautions for this chemical?
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Handling requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. The compound is classified with WGK Germany 3, indicating a high hazard to water.
How is 5-(Dimethylamino)-1-naphthalenesulfonamide packed and shipped?
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Products are carefully packed according to standard chemical handling procedures and exported globally by Tech Serve Solutions, adhering to all relevant shipping regulations for chemical substances.
How can I request a sample or a quote for 5-(Dimethylamino)-1-naphthalenesulfonamide?
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To request a sample or a quote, please contact our sales team through the website or by phone, providing the product name and CAS number (1431-39-6).
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