5-(Di-tert-butylphosphino)-1′, 3′, 5′-triphenyl-1′H-[1,4′]bipyrazole
Tech Serve Solutions (TSS) supplies 5-(Di-tert-butylphosphino)-1′, 3′, 5′-triphenyl-1′H-[1,4′]bipyrazole (CAS: 894086-00-1), a non-proprietary phosphine ligand with the molecular formula C32H35N4P. This compound is primarily utilised as a ligand in palladium-catalyzed cross-coupling reactions, particularly for the amination of aryl halides, including aryl chlorides. It is recognised for its efficacy in facilitating these crucial synthetic transformations in organic chemistry.
- IUPAC
- BippyPhos
- Synonyms
- 4′]bipyrazole,894086-00-1, C32H35N4P
![5-(Di-tert-butylphosphino)-1′, 3′, 5′-triphenyl-1′H-[1,4′]bipyrazole (C32H35N4P) — chemical structure, CAS 894086-00-1; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F894086-00-1.png&w=3840&q=75)
Palladium-Catalyzed Aminations
This ligand is employed in palladium-catalyzed amination reactions of aryl halides, notably including aryl chlorides. It is particularly effective when paired with palladium sources such as Pd₂(dba)₃.
Buchwald-Hartwig Cross Coupling
The compound serves as a non-proprietary phosphine ligand in Buchwald-Hartwig amination reactions, a fundamental method for forming carbon-nitrogen bonds.
General Cross-Coupling Reactions
Its structural features make it a versatile ligand for various palladium-catalyzed cross-coupling reactions, contributing to efficient bond formation in organic synthesis.
| Molecular weight | 506.62 |
|---|---|
| Empirical formula | C32H35N4P |
| Assay | 97% |
| Application | Non-proprietary ligand for palladium-catalyzed amination of aryl halides including aryl chlorides. Works best when the palladium source is Pd2(dba)3 (328774).1 |
| Melting point | 169-173 °C |
| Ligand For | AmidationsBuchwald-Hartwig Cross Coupling ReactionCoupling Reactions |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-(Di-tert-butylphosphino)-1′, 3′, 5′-triphenyl-1′H-[1,4′]bipyrazole used for?
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This compound is used as a non-proprietary phosphine ligand in palladium-catalyzed amination reactions, including the amination of aryl halides such as aryl chlorides, and in general cross-coupling reactions.
What are the CAS number and molecular formula for this chemical?
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The CAS number is 894086-00-1, and the molecular formula is C32H35N4P.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product at a minimum purity of 97%. TSS does not represent this product as USP, BP, or EP grade.
What are the safety considerations when handling this compound?
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This compound has a WGK (German Water Hazard Class) of 3, indicating it is hazardous to water. Appropriate safety precautions and personal protective equipment should be used during handling.
How is this chemical packed, shipped, and exported?
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As a specialist global supplier and exporter, TSS ensures appropriate packaging and handling for international shipment, adhering to all relevant regulations for chemical exports.
How can I request a sample or a quote for this product?
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Please contact our sales team directly through our website or by phone to request a sample or obtain a quotation for this chemical.
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