5-Bromocytosine
5-Bromocytosine (CAS: 2240-25-7, Formula: C4H4BrN3O, MW: 190.00) is a halogenated heterocyclic compound supplied by Tech Serve Solutions. This pyrimidine derivative serves as a crucial building block in chemical synthesis, particularly in the creation of cross-linked nucleic acid analogues. Its applications are primarily within research and development settings for specialised chemical transformations.
- IUPAC
- 4-Amino-5-bromo-2-hydroxypyrimidine

Synthesis of Cross-linked Nucleic Acid Analogues
5-Bromocytosine is employed in the synthesis of various cross-linked products, such as C[5-N6]A, C[5-2]A, C[5-8]A, A[2-5]C, and A[8-5]C. These syntheses can be conducted under both aerobic and anaerobic conditions, highlighting its versatility in organic chemistry research.
Chemical Synthesis Intermediate
As a halogenated heterocycle, 5-Bromocytosine is a valuable intermediate for introducing specific functional groups into more complex molecules. It is utilised in advanced chemical synthesis pathways for research purposes.
Heterocyclic Building Block
This compound functions as a key heterocyclic building block, offering a brominated pyrimidine core for the construction of novel chemical entities and for structure-activity relationship studies.
| Molecular weight | 190.00 |
|---|---|
| Empirical formula | C4H4BrN3O |
| Assay | 99% |
| Application | 5-Bromocytosine was used in the synthesis of five cross-link products- C[5-N6]A, C[5-2]A, C[5-8]A, A[2-5]C, and A[8-5]C, under both aerobic and anaerobic conditions1. |
| Melting point | 240-243 °C (dec.)(lit.) |


Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H317May cause an allergic skin reaction
- H318Causes serious eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-37/38-41-43 |
| Safety statements (S) | 26-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Bromocytosine used for?
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5-Bromocytosine is primarily used as a chemical intermediate and building block in organic synthesis, notably for creating cross-linked nucleic acid analogues and other complex heterocyclic compounds.
What are the CAS number and formula for 5-Bromocytosine?
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The CAS number for 5-Bromocytosine is 2240-25-7, and its molecular formula is C4H4BrN3O.
What grade and purity does Tech Serve Solutions supply for 5-Bromocytosine?
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Tech Serve Solutions supplies 5-Bromocytosine with an assay of 99%. This product is intended for research and chemical synthesis purposes; it is not supplied as USP, BP, EP, or any other pharmacopoeial grade.
How should 5-Bromocytosine be handled?
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5-Bromocytosine is a dangerous substance. It is harmful if swallowed, causes skin irritation, may cause an allergic skin reaction, causes serious eye damage, and may cause respiratory irritation. Handle with appropriate personal protective equipment, including gloves, eye protection, and respiratory protection, in a well-ventilated area.
Can Tech Serve Solutions export 5-Bromocytosine?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 5-Bromocytosine, serving customers worldwide.
How can I get a quote or request a sample of 5-Bromocytosine?
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To request a quote or a sample of 5-Bromocytosine, please contact our sales team through the website or by phone.
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