5α-Androstane-3α,17β-diol
5α-Androstane-3α,17β-diol (CAS: 1852-53-5), with the molecular formula C19H32O2 and a molecular weight of 292.46 g/mol, is a metabolite of testosterone. This compound has demonstrated significant potential in inhibiting the growth of various cancer cell lines while exhibiting minimal toxicity towards normal cells, suggesting its utility in biochemical research and the exploration of novel therapeutic agents.
- IUPAC
- 3α,17β-Dihydroxy-5α-androstane,Dihydroandrosterone
- Synonyms
- 3α,17β-Dihydroxy-5α-androstaneDihydroandrosterone
Cancer Research
5α-Androstane-3α,17β-diol has been investigated for its ability to inhibit the proliferation of multiple cancer cell lines. Its selective toxicity profile, with weak effects on normal cells, makes it a subject of interest for potential anti-cancer research.
Steroid Metabolism Studies
As a metabolite of testosterone, this compound is valuable for researchers studying androgen metabolism pathways. It aids in understanding the biological transformations and effects of steroid hormones within cellular systems.
Cell Biology and Signaling
This diol serves as a tool in cell biology research, particularly in studies related to cell signaling pathways influenced by steroid hormones. Its interaction with cellular mechanisms can provide insights into gene expression and cellular responses.
| Molecular weight | 292.46 |
|---|---|
| Empirical formula | C19H32O2 |
| Application | 5α-Androstane-3α,17β-diol (dihydroandrosterone) is a testosterone metabolite. Dihyroandrosterone inhibited the cell growth of seven cancer cell lines while showing weak toxicity on normal cell lines. |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Drug Control | USDEA Schedule III; Home Office Schedule 4.2; regulated under CDSA - not available from Canada |
|---|---|
| Gene Information | rat ... Ar(24208) |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5α-Androstane-3α,17β-diol used for?
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5α-Androstane-3α,17β-diol is primarily used in research for its demonstrated ability to inhibit the growth of various cancer cell lines and for studies related to steroid metabolism and cell signaling pathways.
What is the CAS number and molecular formula for 5α-Androstane-3α,17β-diol?
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The CAS number is 1852-53-5, and the molecular formula is C19H32O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical as a research-grade compound. The specific assay and purity are available on the Certificate of Analysis, and it is not represented as USP, BP, or EP grade.
How should 5α-Androstane-3α,17β-diol be handled?
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Handling requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Consult the Safety Data Sheet for full details.
Is 5α-Androstane-3α,17β-diol a controlled substance?
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Yes, this compound is regulated under USDEA Schedule III and Home Office Schedule 4.2. It is also regulated under CDSA and not available from Canada.
How is this product exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals. Please contact us for specific export details and to discuss your requirements.
How can I request a sample or quote?
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To request a sample or a quote for 5α-Androstane-3α,17β-diol, please contact our sales department through the website or by phone.
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