5-Amino-2-methylindole
5-Amino-2-methylindole (CAS 7570-49-2) is a versatile chemical intermediate with the molecular formula C9H10N2 and a molecular weight of 146.19 g/mol. This indole derivative serves as a key building block in organic synthesis, particularly for the creation of complex molecules. Its primary applications lie in the development of various pharmaceutical agents, including cytotoxic compounds, antimicrobial candidates, and enzyme inhibitors.
- IUPAC
- 2-Methylindol-5-ylamine
- Synonyms
- 2-Methylindol-5-ylamine
Synthesis of Cytotoxic and Antimitotic Agents
5-Amino-2-methylindole is utilised as a precursor in the synthesis of cytotoxic and antimitotic agents, contributing to the development of potential cancer therapeutics.
Development of Antimicrobial Compounds
This compound is employed in the preparation of potential antimicrobial aminoketones, addressing the need for novel antibacterial and antifungal agents.
Preparation of Enzyme Inhibitors
It functions as a crucial reactant in synthesising various enzyme inhibitors, including those targeting monoamine oxidase (MAO), protein kinase c theta (PKCθ), Factor Xa, and vascular endothelial growth factor type 2 (VEGFR-2).
| Molecular weight | 146.19 |
|---|---|
| Empirical formula | C9H10N2 |
| Assay | 97% |
| Application | Reactant for preparation of:• Cytotoxic and antimitotic agents1• Potential antimicrobial aminoketones2• Inhibitors of monoamine oxidase (MAO)3• Protein kinase c theta (PKCθ) inhibitors4• Factor Xa inhibitors5• Inhibitors of vascular endothelial growth factor type 2 (VEGFR-2)6• Demethylasterriquinone B1receptor ligands7 |
| Melting point | 153-157 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Amino-2-methylindole used for?
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5-Amino-2-methylindole is primarily used as a reactant in chemical synthesis for the preparation of cytotoxic and antimitotic agents, potential antimicrobial aminoketones, and various enzyme inhibitors such as MAO, PKCθ, Factor Xa, and VEGFR-2 inhibitors.
What are the CAS number and chemical formula for 5-Amino-2-methylindole?
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The CAS number for 5-Amino-2-methylindole is 7570-49-2, and its chemical formula is C9H10N2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 5-Amino-2-methylindole with a minimum purity of 97%. This product is supplied for research and chemical synthesis purposes and is not represented as USP, BP, EP, or any other pharmacopoeia grade.
How should 5-Amino-2-methylindole be handled?
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Handling requires appropriate personal protective equipment including a dust mask type N95 (US), eyeshields, and gloves. Avoid breathing dust. In case of contact with eyes, rinse cautiously with water for several minutes and seek medical advice if irritation persists. Ensure adequate ventilation.
Does Tech Serve Solutions export 5-Amino-2-methylindole?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 5-Amino-2-methylindole.
How can I request a sample or quote for 5-Amino-2-methylindole?
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To request a sample or quote, please contact our sales team via the website or directly by phone. Please provide your contact details and the required quantity.
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