5-Amino-1,3,4-thiadiazole-2-thiol
5-Amino-1,3,4-thiadiazole-2-thiol (CAS: 2349-67-9) is a heterocyclic organic compound with the molecular formula C2H3N3S2 and a molecular weight of 133.20 g/mol. This chemical serves as a valuable building block in organic synthesis, particularly for the creation of novel heterocyclic compounds. Its structure lends itself to further chemical modifications for research and development purposes.
- IUPAC
- 2-Amino-5-mercapto-1,3,4-thiadiazole
- Synonyms
- 2349-67-9C2H3N3S22-Amino-5-mercapto-1,3,4-thiadiazole

Pharmaceutical Intermediate Synthesis
5-Amino-1,3,4-thiadiazole-2-thiol is utilised in the synthesis of new chemical entities. Research indicates its use in preparing amines with potential anti-convulsant activity.
Heterocyclic Compound Development
As a thiadiazole derivative, this compound is a key starting material for constructing more complex heterocyclic ring systems, which are prevalent in medicinal chemistry and materials science.
Chemical Research and Synthesis
This molecule functions as a versatile building block in general organic synthesis, enabling chemists to explore novel reaction pathways and develop new molecular architectures.
| Molecular weight | 133.20 |
|---|---|
| Empirical formula | C2H3N3S2 |
| Assay | 98% |
| Application | 5-amino-1,3,4-thiadiazole-2-thiol was used to prepare new amines exhibiting anti-convulsant activity1. |
| Melting point | 235 °C (dec.)(lit.) |

Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Amino-1,3,4-thiadiazole-2-thiol used for?
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5-Amino-1,3,4-thiadiazole-2-thiol is primarily used as a building block in organic synthesis, particularly for the preparation of amines with potential anti-convulsant activity and the development of other heterocyclic compounds.
What are the CAS number and molecular formula for 5-Amino-1,3,4-thiadiazole-2-thiol?
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The CAS number for 5-Amino-1,3,4-thiadiazole-2-thiol is 2349-67-9, and its molecular formula is C2H3N3S2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 5-Amino-1,3,4-thiadiazole-2-thiol with an assay of 98%. We do not represent this product as USP, BP, or EP grade.
What are the safety and handling precautions for this chemical?
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This compound is classified with a Warning signal word and carries hazard statements H302 (Harmful if swallowed), H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Recommended personal protective equipment includes a dust mask type N95 (US), eyeshields, and gloves. Handle in a well-ventilated area.
How is 5-Amino-1,3,4-thiadiazole-2-thiol shipped and exported?
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Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 5-Amino-1,3,4-thiadiazole-2-thiol, adhering to all relevant shipping and export regulations.
How can I request a sample or quote?
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To request a sample or a quotation for 5-Amino-1,3,4-thiadiazole-2-thiol, please contact our sales department through the designated channels on our website.
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