4-Vinylphenylboronic acid MIDA ester
4-Vinylphenylboronic acid MIDA ester (CAS 1257648-79-5, C13H14BNO4) is a versatile aryl MIDA boronate reagent. With a molecular weight of 259.07 g/mol, it is a key intermediate in organic synthesis. This compound is particularly valuable for Suzuki-Miyaura cross-coupling reactions, enabling the formation of carbon-carbon bonds. Its MIDA ester protection offers enhanced stability and handling properties compared to the free boronic acid, making it a reliable choice for advanced chemical synthesis.
- IUPAC
- 6-Methyl-2-(4-vinylphenyl)-1,3,6,2-dioxazaborocane-4,8-dione

Suzuki Cross-Coupling Reactions
4-Vinylphenylboronic acid MIDA ester is an excellent coupling partner in palladium-catalyzed Suzuki-Miyaura cross-coupling reactions. It facilitates the synthesis of biaryl compounds and other complex organic structures.
MIDA Boronate Chemistry
As a member of the MIDA boronate family, this compound offers improved stability and ease of handling. It participates in various cross-coupling protocols, including those that benefit from the controlled release of the boronic acid moiety.
Organic Synthesis Intermediate
This reagent serves as a valuable building block in the multi-step synthesis of pharmaceuticals, agrochemicals, and advanced materials. Its vinyl group offers a handle for further functionalization.
| Molecular weight | 259.07 |
|---|---|
| Empirical formula | C13H14BNO4 |
| Assay | 97% |
| Application | Suzuki Cross-Coupling with MIDA Boronates |
| Melting point | 198-204 °C |

Hazard statements
- H302Harmful if swallowed
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Transport (UN / ADR) | UN 3335 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Vinylphenylboronic acid MIDA ester used for?
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4-Vinylphenylboronic acid MIDA ester is primarily used as a reagent in Suzuki-Miyaura cross-coupling reactions for the synthesis of complex organic molecules, including pharmaceuticals and materials.
What is the CAS number and formula for 4-Vinylphenylboronic acid MIDA ester?
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The CAS number is 1257648-79-5 and the empirical formula is C13H14BNO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Vinylphenylboronic acid MIDA ester with an assay of 97%. We do not represent this product as USP, BP, or EP grade.
How should 4-Vinylphenylboronic acid MIDA ester be handled?
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Handling requires a dust mask (NIOSH N95 or equivalent), eyeshields, and gloves. Ensure adequate ventilation as it is harmful if swallowed (H302).
How is 4-Vinylphenylboronic acid MIDA ester packed and shipped?
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This chemical is packed and exported according to international regulations for hazardous materials (UN 3335). Specific packing details can be provided upon request.
How can I request a quote or sample?
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To request a quote or sample, please use the contact form on our website or call our sales department, referencing the product name and CAS number.
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