4-(Trifluoromethylthio)benzylamine
4-(Trifluoromethylthio)benzylamine (CAS: 128273-56-3; Formula: CF3SC6H4CH2NH2) is a valuable organic compound with a molecular weight of 207.22 g/mol. This amine-containing molecule serves as a crucial building block in chemical synthesis. Its structure, featuring both a trifluoromethylthio group and a benzylamine moiety, makes it useful for introducing specific functional groups in the development of complex organic molecules and advanced materials.

Organic Synthesis
Utilised as a key intermediate and building block in multi-step organic synthesis pathways. Its reactive amine group allows for facile derivatization and incorporation into larger molecular structures.
Pharmaceutical Research
Serves as a precursor in the research and development of novel pharmaceutical agents. The trifluoromethylthio group can influence pharmacokinetic properties, making it an attractive moiety for drug discovery.
Materials Science
Employed in the synthesis of specialised polymers and functional materials where the unique electronic and steric properties of the trifluoromethylthio group are desired.
| Molecular weight | 207.22 |
|---|---|
| Linear formula | CF3SC6H4CH2NH2 |
| Assay | 97% |
| Boiling point | 224-225 °C/760 mmHg(lit.) |
| Density | 1.310 g/mL(lit.) |
| Refractive index | n20/D 1.5040(lit.) |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 79 °C / 174.2 °F |
| Transport (UN / ADR) | UN 3267 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-27-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-(Trifluoromethylthio)benzylamine used for?
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4-(Trifluoromethylthio)benzylamine is primarily used as a building block in organic synthesis, particularly in the research and development of pharmaceuticals and advanced materials.
What are the CAS number and chemical formula?
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The CAS number is 128273-56-3, and the chemical formula is CF3SC6H4CH2NH2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-(Trifluoromethylthio)benzylamine with an assay of 97%. This compound is supplied for research and laboratory use, and is not represented as USP, BP, EP, or any other pharmacopoeia grade.
How should 4-(Trifluoromethylthio)benzylamine be handled safely?
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Handling requires extreme caution. This substance is corrosive (H314) and causes severe skin burns and eye damage. Appropriate personal protective equipment, including full-face respirators, chemical-resistant gloves, and eye protection, must be worn. Work in a well-ventilated area or fume hood. Refer to the Safety Data Sheet for comprehensive handling and emergency procedures.
Is 4-(Trifluoromethylthio)benzylamine suitable for export?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 4-(Trifluoromethylthio)benzylamine, adhering to all international shipping regulations.
How can I request a sample or quote?
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To request a sample or a quotation for 4-(Trifluoromethylthio)benzylamine, please contact our sales team through the website or by phone, providing your specific requirements.
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