4-Phenylbutyryl hydroxamic acid
4-Phenylbutyryl hydroxamic acid (CAS: 32153-46-1, C10H13NO2) is a potent inhibitor of histone deacetylase (HDH) enzymes. This white to tan powder with a molecular weight of 179.22 g/mol is primarily utilized in biochemical research for studying gene expression and cellular differentiation. Its solubility in water makes it convenient for various in vitro experimental setups. Available with a purity of ≥98%, it is supplied by TSS under standard laboratory conditions.
Histone Deacetylase (HDAC) Inhibition
4-Phenylbutyryl hydroxamic acid acts as a specific inhibitor of histone deacetylase enzymes, crucial for regulating gene expression and cellular processes. It is widely used in research to explore the epigenetic mechanisms underlying various biological functions and diseases.
Cell Biology Research
This compound is instrumental in cell biology studies investigating pathways related to cell cycle progression, differentiation, and apoptosis. Its ability to modulate chromatin structure provides insights into cellular responses to various stimuli.
Gene Expression Studies
Researchers employ 4-Phenylbutyryl hydroxamic acid to study the effects of HDAC inhibition on DNA-RNA transcription and gene regulation. It aids in understanding how post-translational modifications of histones influence the accessibility of DNA and gene expression patterns.
Neuroscience Research Tool
In neuroscience, this hydroxamic acid derivative is used to investigate the role of histone acetylation in neuronal function, development, and neurodegenerative disorders. It serves as a valuable tool for exploring epigenetic modifications in the central nervous system.
| Molecular weight | 179.22 |
|---|---|
| Empirical formula | C10H13NO2 |
| Assay | ≥98% (HPLC) |
| Form | powder |
| Colour | white to tan |
| Solubility | H2O: ≥10 mg/mL |
| Storage temperature | 2-8°C |
Hazard statements
- H302Harmful if swallowed
- H319Causes serious eye irritation
Precautionary statements
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Shipped In | wet ice |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Phenylbutyryl hydroxamic acid used for?
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4-Phenylbutyryl hydroxamic acid is primarily used in biochemical and cell biology research as a histone deacetylase (HDAC) inhibitor to study gene expression, cellular differentiation, and epigenetic regulation. It is also applied in neuroscience research.
What are the CAS number and formula for 4-Phenylbutyryl hydroxamic acid?
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The CAS number for 4-Phenylbutyryl hydroxamic acid is 32153-46-1, and its empirical formula is C10H13NO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Phenylbutyryl hydroxamic acid with a purity of ≥98% (HPLC). This product is intended for laboratory and research use and is not represented as USP, BP, or EP grade.
What are the safety and handling precautions for 4-Phenylbutyryl hydroxamic acid?
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4-Phenylbutyryl hydroxamic acid is classified with GHS07 symbol and a Warning signal word. It carries hazard statements H302 (Harmful if swallowed) and H319 (Causes serious eye irritation). Handle with appropriate personal protective equipment, avoid contact with skin and eyes, and ensure adequate ventilation. In case of eye contact, rinse cautiously with water for several minutes. If swallowed, seek medical advice.
How is 4-Phenylbutyryl hydroxamic acid shipped and stored?
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This product is shipped in wet ice and should be stored at a temperature of 2-8°C to maintain its stability and quality.
How can I request a quote or sample for 4-Phenylbutyryl hydroxamic acid?
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To request a quote or sample of 4-Phenylbutyryl hydroxamic acid, please contact our sales department via the website or by phone, providing your specific requirements and shipping details.
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