4-Phenyl-1,3-dioxane
4-Phenyl-1,3-dioxane (CAS: 772-00-9), a cyclic acetal with the molecular formula C10H12O2, is a valuable organic building block. Its structure facilitates its use in chemical synthesis as a protected form of a diol or as a precursor in various organic reactions. This compound is typically supplied for research and industrial synthesis purposes, offering a reliable intermediate for chemists.
- Synonyms
- C10H12O2

Organic Synthesis Intermediate
4-Phenyl-1,3-dioxane serves as a versatile intermediate in the synthesis of more complex organic molecules. Its protected hydroxyl groups can be selectively deprotected or further functionalized.
Building Block for Heterocycles
The dioxane ring system can be incorporated into larger heterocyclic structures or modified to create diverse chemical scaffolds relevant to pharmaceutical and material science research.
Protecting Group Chemistry
It can be employed as a stable protecting group for 1,3-diols during multi-step synthetic sequences, preventing unwanted reactions at these sites.
| Molecular weight | 164.20 |
|---|---|
| Empirical formula | C10H12O2 |
| Assay | 98% |
| Boiling point | 250-251 °C(lit.) |
| Density | 1.111 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.53(lit.) |

Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Phenyl-1,3-dioxane used for?
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4-Phenyl-1,3-dioxane is primarily used as a building block and intermediate in organic synthesis, including applications in protecting group chemistry and the construction of heterocyclic compounds.
What is the CAS number and formula for 4-Phenyl-1,3-dioxane?
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The CAS number is 772-00-9 and the empirical formula is C10H12O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Phenyl-1,3-dioxane with an assay of 98%. This product is suitable for general chemical synthesis and research purposes; TSS does not represent it as USP, BP, or EP grade.
What are the primary safety concerns when handling 4-Phenyl-1,3-dioxane?
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This compound is classified as harmful if swallowed, causes skin irritation, eye irritation, and may cause respiratory irritation (H302, H315, H319, H335). Appropriate personal protective equipment, including eyeshields, gloves, and suitable respiratory protection, should be used.
Is 4-Phenyl-1,3-dioxane available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 4-Phenyl-1,3-dioxane.
How can I request a sample or quote for 4-Phenyl-1,3-dioxane?
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Please contact our sales department through the website or by phone to request a sample or a detailed quotation for 4-Phenyl-1,3-dioxane.
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