4-Pentyn-1-amine
4-Pentyn-1-amine (CAS: 15252-44-5), with the molecular formula H₂NCH₂CH₂C≡CH and a molecular weight of 83.13 g/mol, is a primary amine featuring a terminal alkyne functionality. This unique structure makes it a valuable building block in organic synthesis. It is commonly employed in chemical biology and conjugation chemistry, particularly in reactions involving azides and alkynes.
- IUPAC
- 1-Amino-4-pentyne,4-Pentynylamine,5-Amino-1-pentyne
- Synonyms
- 1-Amino-4-pentyne4-Pentynylamine5-Amino-1-pentyne

Organic Synthesis Building Block
4-Pentyn-1-amine serves as a versatile building block for constructing more complex organic molecules. The presence of both an amine and a terminal alkyne allows for diverse synthetic transformations and functionalization.
Conjugation Chemistry
This compound is utilised in conjugation chemistry, particularly in click chemistry reactions like the copper-catalysed azide-alkyne cycloaddition (CuAAC), enabling the efficient linking of molecules.
Chemical Biology Research
Researchers in chemical biology may use 4-Pentyn-1-amine for bioconjugation, labelling, or developing probes for biological systems due to its reactive functional groups.
| Molecular weight | 83.13 |
|---|---|
| Linear formula | H2NCH2CH2C≡CH |
| Assay | ≥94.0% (NT) |
| Density | 0.859 g/mL at 20 °C |
| Storage temperature | 2-8°C |
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Pentyn-1-amine used for?
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4-Pentyn-1-amine is primarily used as a building block in organic synthesis, in conjugation chemistry (e.g., click chemistry), and in chemical biology research for applications such as bioconjugation and labelling.
What is the CAS number and formula for 4-Pentyn-1-amine?
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The CAS number for 4-Pentyn-1-amine is 15252-44-5, and its molecular formula is H₂NCH₂CH₂C≡CH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Pentyn-1-amine with an assay of ≥94.0% (NT). TSS does not represent this product as USP, BP, EP, or other pharmacopoeial grades.
What are the safety and handling considerations for 4-Pentyn-1-amine?
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4-Pentyn-1-amine is a flammable liquid and vapour. It causes serious eye irritation and may cause respiratory irritation. It is recommended to keep it away from heat, hot surfaces, sparks, open flames, and other ignition sources. Wear protective gloves and eye protection. Refer to the Safety Data Sheet (SDS) for comprehensive handling information.
How is 4-Pentyn-1-amine packaged and exported?
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4-Pentyn-1-amine is packaged according to standard chemical handling procedures to ensure safety during transport. Tech Serve Solutions is a global supplier and exporter of fine chemicals.
How can I request a sample or quote for 4-Pentyn-1-amine?
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To request a sample or a quotation for 4-Pentyn-1-amine, please contact the Tech Serve Solutions sales team through the website or via direct inquiry.
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