4-Methylpyridine
4-Methylpyridine (CAS 108-89-4), with the molecular formula C6H7N, is a colourless to pale yellow liquid with a characteristic pyridine odour. It is a versatile heterocyclic compound used primarily as a building block in chemical synthesis. Its applications span the preparation of various organic compounds, including specialised derivatives. Tech Serve Solutions supplies 4-Methylpyridine with an assay of 98% for research and industrial purposes.
- IUPAC
- 4-Methylpyridine,4-Picoline
- Synonyms
- 4-Picoline

Chemical Synthesis Intermediate
4-Methylpyridine serves as a crucial intermediate in organic synthesis. It is employed in the preparation of more complex molecules, contributing to the development of novel compounds and materials.
Preparation of Dihydropyridine Derivatives
This compound has been documented for its use in the preparation of 1,2-dihydropyridide derivatives, showcasing its utility in specialised heterocyclic chemistry.
Research and Development
As a fundamental pyridine derivative, 4-Methylpyridine is widely utilised in laboratory settings for research and development projects across various chemical disciplines.
| Molecular weight | 93.13 |
|---|---|
| Empirical formula | C6H7N |
| Assay | 98% |
| Boiling point | 145 °C(lit.) |
| Density | 0.957 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.504(lit.) |
| Vapour pressure | 4 mmHg (20 °C) |
| Melting point | 2.4 °C(lit.) |
| Vapour density | 3.2 (vs air) |
| Autoignition temp | 1000 °F |
| Application | 4-Methylpyridine was used in the preparation of a 1,2-dihydropyridide derivative1. |


Hazard statements
- H226Flammable liquid and vapour
- H302Harmful if swallowed
- H311Toxic in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P312Call a POISON CENTER if you feel unwell
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 39 °C / 102.2 °F |
| Transport (UN / ADR) | UN 2313 3 / PGIII |
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | T |
| Risk statements (R) | 10-20/22-24-36/37/38 |
| Safety statements (S) | 26-36-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Methylpyridine used for?
+
4-Methylpyridine is used as a building block in chemical synthesis, particularly in the preparation of dihydropyridine derivatives and other specialised organic compounds in research and development.
What are the CAS number and formula for 4-Methylpyridine?
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The CAS number for 4-Methylpyridine is 108-89-4, and its molecular formula is C6H7N.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Methylpyridine with an assay of 98%. This is a technical grade product and is not represented as USP, BP, or EP grade.
How should 4-Methylpyridine be handled safely?
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4-Methylpyridine is a flammable liquid and vapour (H226), harmful if swallowed (H302), toxic in contact with skin (H311), and harmful if inhaled (H332). It also causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Always wear appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator, and handle in a well-ventilated area. Refer to the Safety Data Sheet for full details.
Is 4-Methylpyridine a controlled substance?
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The provided data does not indicate that 4-Methylpyridine is a controlled substance.
How is 4-Methylpyridine packed and shipped?
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4-Methylpyridine is shipped as UN 2313, Hazard Class 3, Packing Group III. Specific packing and export details are available upon request.
How can I request a quote or sample for 4-Methylpyridine?
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To request a quote or sample for 4-Methylpyridine, please contact the Tech Serve Solutions sales team directly through our website or by phone.
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