[(4-methylpiperazin-1-ium-1-yl)methyl]trifluoroborate
[(4-methylpiperazin-1-yl)methyl]trifluoroborate (CAS: 1268340-98-2, Formula: C6H14BF3N2) is an organotrifluoroborate salt with a molecular weight of 181.99 g/mol. This compound serves as a valuable reagent in organic synthesis, particularly noted for its utility in Suzuki-Miyaura cross-coupling reactions and for coupling with activated organic substrates. Its stability makes it an attractive alternative to traditional boronic acids in various synthetic methodologies.
![[(4-methylpiperazin-1-ium-1-yl)methyl]trifluoroborate (C6H14BF3N2) — chemical structure, CAS 1268340-98-2; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F1268340-98-2.png&w=3840&q=75)
Suzuki-Miyaura Cross-Coupling Reactions
This organotrifluoroborate is employed as a coupling partner in Suzuki-Miyaura reactions, facilitating the formation of carbon-carbon bonds. It offers a stable and convenient alternative to corresponding boronic acids in these palladium-catalysed cross-coupling processes.
Cross-Coupling with Activated Species
The compound participates in cross-coupling reactions with activated organic molecules, such as mesylated phenol derivatives. This application expands its utility in the synthesis of complex organic structures.
Chemical Synthesis Reagent
Utilised as a versatile building block in general chemical synthesis, [(4-methylpiperazin-1-yl)methyl]trifluoroborate enables the introduction of specific functional groups. Its trifluoroborate moiety contributes to its reactivity and stability profile.
| Molecular weight | 181.99 |
|---|---|
| Empirical formula | C6H14BF3N2 |
| Application | Organotrifluoroborate involved in Suzuki-Miyaura cross-coupling reactions1 and cross coupling with mesylated phenol derivatives2Organotrifluoroborates as versatile and stable boronic acid surrogates. |
| Melting point | 64-70 °C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is [(4-methylpiperazin-1-yl)methyl]trifluoroborate used for?
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[(4-methylpiperazin-1-yl)methyl]trifluoroborate is primarily used in organic synthesis, notably in Suzuki-Miyaura cross-coupling reactions and for coupling with activated organic substrates like mesylated phenol derivatives. It acts as a stable organotrifluoroborate reagent.
What is the CAS number and chemical formula for this compound?
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The CAS number for [(4-methylpiperazin-1-yl)methyl]trifluoroborate is 1268340-98-2, and its chemical formula is C6H14BF3N2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical for research and laboratory use. The specific grade and purity are available upon request; we do not represent this product as meeting USP, BP, or EP pharmacopoeial standards.
What are the main safety hazards associated with this chemical?
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This compound is classified as a Warning. It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Handle with appropriate personal protective equipment in a well-ventilated area.
How is this product packed, shipped, and exported?
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Tech Serve Solutions packs and ships chemicals in compliance with all relevant national and international regulations for hazardous materials. We are experienced global exporters.
How can I request a sample or obtain a quote?
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To request a sample or obtain a quotation, please contact our sales department via the website or by telephone, providing the product name and CAS number (1268340-98-2).
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