4-Methoxybenzenesulfonyl chloride
4-Methoxybenzenesulfonyl chloride (CAS: 98-68-0; Formula: CH3OC6H4SO2Cl; MW: 206.65) is a key organic building block and sulfonyl halide. It is a versatile intermediate employed in various chemical syntheses, particularly for the introduction of the 4-methoxybenzenesulfonyl group into organic molecules. This compound serves as a valuable reagent in research and development and industrial chemical production, contributing to the synthesis of diverse chemical entities.

Organic Synthesis
Serves as a crucial reagent for introducing the 4-methoxybenzenesulfonyl moiety in organic transformations. It is widely used in the synthesis of pharmaceuticals, agrochemicals, and specialty organic compounds.
Pharmaceutical Intermediates
Acts as a building block in the multi-step synthesis of active pharmaceutical ingredients (APIs). Its reactivity allows for the construction of complex molecular architectures relevant to drug discovery and development.
Material Science
May be utilised in the development of novel materials and polymers where the introduction of specific sulfonyl groups can impart desired properties. Its application in this field is an area of ongoing research.
| Molecular weight | 206.65 |
|---|---|
| Linear formula | CH3OC6H4SO2Cl |
| Assay | 99% |
| Boiling point | 173 °C/14 mmHg(lit.) |
| Storage temperature | 2-8°C |
| Melting point | 39-42 °C(lit.) |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Flash point | 112 °C / 233.6 °F |
| Transport (UN / ADR) | UN 3261 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Methoxybenzenesulfonyl chloride used for?
+
4-Methoxybenzenesulfonyl chloride is primarily used as a reagent in organic synthesis for introducing the 4-methoxybenzenesulfonyl group, serving as a building block for pharmaceuticals, agrochemicals, and other fine chemicals.
What are the CAS number and chemical formula for 4-Methoxybenzenesulfonyl chloride?
+
The CAS number is 98-68-0, and the chemical formula is CH3OC6H4SO2Cl.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 4-Methoxybenzenesulfonyl chloride with an assay of 99%. This product is supplied for research and industrial purposes and is not represented as USP, BP, EP, or any other pharmacopoeia grade.
How should 4-Methoxybenzenesulfonyl chloride be handled?
+
4-Methoxybenzenesulfonyl chloride is a corrosive substance (GHS05, Danger, H314). Handle with extreme caution, using appropriate personal protective equipment including eyeshields, face shields, and chemical-resistant gloves. Ensure adequate ventilation or use a respirator. Store at 2-8°C.
How is 4-Methoxybenzenesulfonyl chloride packed and exported?
+
This compound is shipped as a hazardous material, UN 3261, Class 8, Packing Group II. Tech Serve Solutions adheres to all international shipping regulations for the safe export of chemicals.
How can I request a quote or sample for 4-Methoxybenzenesulfonyl chloride?
+
To request a quote or sample of 4-Methoxybenzenesulfonyl chloride, please contact our sales department via the website or email, providing your contact details and the quantity required.
▶ Related products

1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis

1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis