4-Mercaptophenol
4-Mercaptophenol (CAS 637-89-8) is a sulfur-containing organic compound with the formula HSC6H4OH and a molecular weight of 126.18 g/mol. This thiol and phenol derivative serves as a valuable building block in chemical synthesis. It is particularly useful for introducing thiol or phenolic functionalities into larger molecules, finding applications in organic chemistry research and the development of novel materials and pharmaceutical intermediates.
- IUPAC
- 4-Hydroxythiophenol

Organic Synthesis Intermediate
4-Mercaptophenol acts as a versatile intermediate in the synthesis of complex organic molecules. Its dual functionality allows for diverse reaction pathways in the construction of new chemical entities.
Material Science
The compound can be incorporated into polymers or used in surface modification due to the reactivity of its thiol and hydroxyl groups. This makes it relevant for developing advanced materials with specific properties.
Pharmaceutical Research
As an organic building block, 4-Mercaptophenol is employed in the early stages of drug discovery and development. It aids in the synthesis of potential pharmaceutical ingredients and related compounds.
| Molecular weight | 126.18 |
|---|---|
| Linear formula | HSC6H4OH |
| Assay | 90% |
| Boiling point | 149-150 °C/25 mmHg(lit.) |
| Melting point | 33-35 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Flash point | 110 °C / 230 °F |
|---|---|
| Transport (UN / ADR) | UN 3335 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Mercaptophenol used for?
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4-Mercaptophenol is primarily used as a building block in organic synthesis and in material science research. It is also employed in the development of pharmaceutical intermediates.
What are the CAS number and formula for 4-Mercaptophenol?
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The CAS number for 4-Mercaptophenol is 637-89-8, and its chemical formula is HSC6H4OH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Mercaptophenol with an assay of 90%. We do not represent this product as meeting USP, BP, or EP pharmacopoeia standards.
How should 4-Mercaptophenol be handled safely?
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4-Mercaptophenol is a Warning substance that causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Handle with appropriate personal protective equipment, ensure good ventilation, and avoid contact with eyes, skin, and clothing.
How is 4-Mercaptophenol packed and shipped?
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4-Mercaptophenol is typically packed in compliance with international shipping regulations. TSS exports fine chemicals globally to meet diverse research and industrial needs.
How can I request a quote or sample for 4-Mercaptophenol?
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To request a quote or sample, please contact our sales team through the website or call us directly. We are happy to assist with your chemical sourcing requirements.
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