4-Iodo-2-(trifluoromethyl)benzonitrile
4-Iodo-2-(trifluoromethyl)benzonitrile (CAS: 101066-87-9) is an organic compound with the formula C8H3F3IN. It is a substituted benzonitrile featuring both an iodine atom and a trifluoromethyl group, making it a valuable intermediate in organic synthesis. This chemical is primarily employed as a building block in the development of complex molecules for research and industrial applications.
- IUPAC
- 4-Cyano-3-(trifluoromethyl)iodobenzene
- Synonyms
- 4-Cyano-3-(trifluoromethyl)iodobenzene
Organic Synthesis Intermediate
Serves as a crucial building block for introducing the 2-(trifluoromethyl)benzonitrile moiety into larger organic structures. Its reactivity is leveraged in cross-coupling reactions and other synthetic transformations.
Pharmaceutical Research
Used in the synthesis of novel pharmaceutical candidates and active pharmaceutical ingredients (APIs). The trifluoromethyl group can influence pharmacokinetic properties, while the iodo- and cyano- groups offer synthetic handles.
Materials Science
Potentially applicable in the development of advanced materials where specific electronic or structural properties are desired, stemming from the unique combination of functional groups.
| Molecular weight | 297.02 |
|---|---|
| Empirical formula | C8H3F3IN |
| Assay | 97% |
| Melting point | 50-55 °C |
Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Flash point | >110 °C / >230 °F |
| Transport (UN / ADR) | UN 3439 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38 |
| Safety statements (S) | 26-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Iodo-2-(trifluoromethyl)benzonitrile used for?
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4-Iodo-2-(trifluoromethyl)benzonitrile is primarily used as a building block and intermediate in organic synthesis, particularly in the research and development of pharmaceuticals and advanced materials.
What are the CAS number and formula for 4-Iodo-2-(trifluoromethyl)benzonitrile?
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The CAS number is 101066-87-9, and the chemical formula is C8H3F3IN.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Iodo-2-(trifluoromethyl)benzonitrile with an assay of 97%. This product is typically considered a research or technical grade and is not represented as USP, BP, EP, or any other pharmacopoeia standard.
How should 4-Iodo-2-(trifluoromethyl)benzonitrile be handled safely?
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Based on GHS classification, this compound is harmful if swallowed, inhaled, or in contact with skin, and causes skin and eye irritation, and respiratory irritation. Handle with appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves. Ensure adequate ventilation. Refer to the Safety Data Sheet (SDS) for comprehensive handling instructions.
Is 4-Iodo-2-(trifluoromethyl)benzonitrile a controlled substance?
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The provided data does not indicate that 4-Iodo-2-(trifluoromethyl)benzonitrile is a scheduled or controlled substance.
How is this chemical packed, shipped, and exported?
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This chemical is packed according to standard industry practices for hazardous materials, adhering to UN 3439 6.1 / PGIII regulations for transport. Tech Serve Solutions is experienced in exporting fine chemicals globally.
How can I request a quote or sample?
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Please contact our sales department or use the online inquiry form on the Tech Serve Solutions website to request a quote or sample for 4-Iodo-2-(trifluoromethyl)benzonitrile.
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