4′-Hydroxydiclofenac
4′-Hydroxydiclofenac (CAS 64118-84-9) is a chemical compound with the formula C14H11Cl2NO3 and a molecular weight of 312.15 g/mol. This substance serves as a valuable analytical standard, particularly for determining the activity of CYP2C9 enzymes. Its applications extend into research areas involving cell biology, drug metabolism, and neuroscience, contributing to a deeper understanding of biological processes and xenobiotic interactions.
- IUPAC
- 4′-Hydroxy Diclofenac,[2-(2,6-Dichloro-4-hydroxy-phenylamino)phenyl]acetic acid
CYP2C9 Activity Determination
4′-Hydroxydiclofenac is specifically used as an analytical standard to measure and understand the activity of the Cytochrome P450 2C9 (CYP2C9) isozyme. This is crucial for drug metabolism studies.
Drug and Xenobiotic Metabolism Research
The compound is employed in studies focused on how the body metabolises drugs and foreign substances. It aids in understanding metabolic pathways and enzyme function.
Cell Biology and Signaling Investigations
As a bioactive small molecule, 4′-Hydroxydiclofenac finds application in cell biology research, particularly in investigations related to cell signaling and neuroscience.
| Molecular weight | 312.15 |
|---|---|
| Empirical formula | C14H11Cl2NO3 |
| Assay | ≥98% (HPLC) |
| Storage temperature | −20°C |
| Application | Used for determining CYP2C9 activity, see Cytochrome P450 isozymes. |
Hazard statements
- H301Toxic if swallowed
- H315Causes skin irritation
- H318Causes serious eye damage
- H335May cause respiratory irritation
- H410Very toxic to aquatic life with long-lasting effects
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P273Avoid release to the environment
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P305IF IN EYES
- P501Dispose of contents and container per local regulations
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1/PG 3 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T,N |
| Risk statements (R) | 25-37/38-41-50/53 |
| Safety statements (S) | 26-39-45-60-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Packaging | vial of 5 mg |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4′-Hydroxydiclofenac used for?
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4′-Hydroxydiclofenac is primarily used as an analytical standard for determining the activity of CYP2C9 enzymes and in research related to drug and xenobiotic metabolism, cell biology, and neuroscience.
What are the CAS number and chemical formula for 4′-Hydroxydiclofenac?
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The CAS number for 4′-Hydroxydiclofenac is 64118-84-9, and its chemical formula is C14H11Cl2NO3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4′-Hydroxydiclofenac with a purity of ≥98% (HPLC). We do not represent this product as USP, BP, or EP grade.
How should 4′-Hydroxydiclofenac be handled and stored?
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This compound is classified as Dangerous (GHS05, GHS06, GHS09) and requires careful handling. It is toxic if swallowed, causes skin irritation, causes serious eye damage, and may cause respiratory irritation. It is also very toxic to aquatic life with long-lasting effects. Store at -20°C. Always use appropriate personal protective equipment, including eyeshields, face shields, gloves, and a P2 respirator cartridge.
How is 4′-Hydroxydiclofenac packaged and exported by TSS?
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4′-Hydroxydiclofenac is typically supplied in a vial containing 5 mg. Tech Serve Solutions is a global supplier and exporter of fine chemicals.
How can I request a quote or sample for 4′-Hydroxydiclofenac?
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Please contact our sales team via the website or directly to request a quote or sample for 4′-Hydroxydiclofenac.
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