4-Hydroxy-3,5-dimethylbenzaldehyde
4-Hydroxy-3,5-dimethylbenzaldehyde (CAS 2233-18-3) is a white to off-white crystalline solid. This aromatic aldehyde, with the linear formula HOC₆H₂(CH₃)₂CHO and a molecular weight of 150.17 g/mol, serves as a valuable building block in organic synthesis. It is primarily employed as a reagent in specific polymerisation reactions and as a starting material for the preparation of other organic compounds, including substituted phenols.
- IUPAC
- 3,5-Dimethyl-4-hydroxybenzaldehyde
- Synonyms
- HOC6H2(CH3)2CHO3,5-Dimethyl-4-hydroxybenzaldehyde

Reagent in Polymerisation
4-Hydroxy-3,5-dimethylbenzaldehyde has been utilised as a reagent in the phase transfer catalysed polymerisation of 4-hydroxy-3,5-dimethylbenzyl alcohol. This application highlights its role in the synthesis of specific polymeric materials.
Synthesis of Trimethylphenol
This compound serves as a starting reagent in the synthesis of 2,4,6-trimethylphenol. Its structure lends itself to specific chemical transformations leading to valuable aromatic compounds.
Organic Building Block
As an aldehyde and a substituted phenol, 4-Hydroxy-3,5-dimethylbenzaldehyde functions as a versatile building block in organic chemistry. It is suitable for various chemical synthesis pathways and research applications.
| Molecular weight | 150.17 |
|---|---|
| Linear formula | HOC6H2(CH3)2CHO |
| Assay | 95% |
| Application | 4-Hydroxy-3,5-dimethylbenzaldehydewas used as reagent during the phase transfer catalyzed polymerization of 4-hydroxy-3,5-dimethylbenzyl alcohol1. It was used as starting reagent during the synthesis of 2,4,6-trimethylphenol2. |
| Melting point | 112-114 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Hydroxy-3,5-dimethylbenzaldehyde used for?
+
4-Hydroxy-3,5-dimethylbenzaldehyde (CAS 2233-18-3) is used as a reagent in polymerisation reactions and as a starting material for the synthesis of compounds like 2,4,6-trimethylphenol. It is a valuable building block in organic synthesis.
What is the CAS number and linear formula for 4-Hydroxy-3,5-dimethylbenzaldehyde?
+
The CAS number for 4-Hydroxy-3,5-dimethylbenzaldehyde is 2233-18-3. Its linear formula is HOC₆H₂(CH₃)₂CHO.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 4-Hydroxy-3,5-dimethylbenzaldehyde with an assay of 95%. This product is typically considered a technical or research grade chemical, and TSS does not represent it as USP, BP, or EP grade.
How should 4-Hydroxy-3,5-dimethylbenzaldehyde be handled safely?
+
4-Hydroxy-3,5-dimethylbenzaldehyde is a Warning substance that causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). It requires the use of a dust mask type N95 (US), eyeshields, and gloves. Ensure adequate ventilation and avoid inhaling dust.
Is 4-Hydroxy-3,5-dimethylbenzaldehyde available for export?
+
Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 4-Hydroxy-3,5-dimethylbenzaldehyde. We can facilitate international shipping and export orders.
How can I request a sample or quote for this chemical?
+
To request a sample or a quote for 4-Hydroxy-3,5-dimethylbenzaldehyde, please contact our sales team through the website or by phone. We will be happy to assist you with your inquiry.
▶ Related products

1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis

1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis