4-Ethynylpyridine hydrochloride
4-Ethynylpyridine hydrochloride (CAS: 352530-29-1), with the molecular formula C7H5N · HCl and a molecular weight of 139.58 g/mol, is a vital heterocyclic building block. Supplied by Tech Serve Solutions at a minimum assay of 97%, this compound serves as a versatile reagent in chemical synthesis. It is particularly useful for introducing the 4-pyridyl ethynyl moiety into more complex molecular structures within research and development laboratories.

Organic Synthesis
4-Ethynylpyridine hydrochloride is employed as a key building block in the synthesis of diverse organic molecules. Its ethynyl group allows for participation in various coupling reactions, such as Sonogashira coupling, facilitating the construction of conjugated systems and complex heterocyclic frameworks.
Pharmaceutical Intermediate
This compound can serve as an intermediate in the development of novel pharmaceutical agents. The pyridine core is a common structural motif in many biologically active compounds, and the ethynyl functionality offers a convenient handle for further chemical modification and drug discovery efforts.
Materials Science
The rigid structure and reactive ethynyl group make 4-Ethynylpyridine hydrochloride a potential precursor for functional materials. It may be utilised in the synthesis of polymers, organic semiconductors, or ligands for coordination chemistry, contributing to the development of advanced materials with tailored electronic or optical properties.
| Molecular weight | 139.58 |
|---|---|
| Empirical formula | C7H5N · HCl |
| Assay | 97% |
| Melting point | 150 °C (dec.)(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Ethynylpyridine hydrochloride used for?
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4-Ethynylpyridine hydrochloride is primarily used as a building block in organic synthesis, particularly for creating more complex molecules in pharmaceutical research and materials science.
What is the CAS number and formula for 4-Ethynylpyridine hydrochloride?
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The CAS number for 4-Ethynylpyridine hydrochloride is 352530-29-1, and its empirical formula is C7H5N · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Ethynylpyridine hydrochloride with a minimum assay of 97%. This product is intended for research and chemical synthesis purposes and is not represented as USP, BP, EP, or other pharmacopoeia grades.
How should 4-Ethynylpyridine hydrochloride be handled?
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Handling requires appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves, as it may cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335).
Is 4-Ethynylpyridine hydrochloride a controlled substance?
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Based on the provided data, there is no indication that 4-Ethynylpyridine hydrochloride is a controlled substance.
How is 4-Ethynylpyridine hydrochloride packed and shipped?
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4-Ethynylpyridine hydrochloride is available for purchase and export globally. Specific packing details for shipment can be provided upon request.
How can I request a quote or sample?
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To request a quote or a sample of 4-Ethynylpyridine hydrochloride, please contact our sales team through the website or by phone.
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