4-Cyanobenzylzinc bromide solution
4-Cyanobenzylzinc bromide solution (CAS 135579-87-2), with the linear formula NCC<sub>6</sub>H<sub>4</sub>CH<sub>2</sub>ZnBr and a molecular weight of 261.43 g/mol, is a valuable organozinc reagent. Supplied as a 0.5 M solution in THF, it is primarily utilised in organic synthesis for cross-coupling reactions. Its reactivity makes it a key intermediate in the construction of complex organic molecules, offering precise control in synthetic pathways.
Organozinc Reagent in Cross-Coupling
This organozinc halide is employed in various metal-catalyzed cross-coupling reactions, facilitating the formation of new carbon-carbon bonds. It is particularly useful for introducing the 4-cyanobenzyl group into organic frameworks.
Synthesis of Pharmaceutical Intermediates
The compound serves as a building block in the multi-step synthesis of active pharmaceutical ingredients (APIs) and complex organic molecules with potential biological activity.
Fine Chemical Synthesis
Used in the development and production of fine chemicals where precise functionalization and structural complexity are required.
| Molecular weight | 261.43 |
|---|---|
| Linear formula | NCC6H4CH2ZnBr |
| Density | 0.956 g/mL at 25 °C |
| Concentration | 0.5 M in THF |
| Storage temperature | 2-8°C |
Hazard statements
- H225Highly flammable liquid and vapour
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H351Suspected of causing cancer
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P281Use personal protective equipment as required
- P305IF IN EYES
| Flash point | -17 °C / 1.4 °F |
|---|---|
| Transport (UN / ADR) | UN 2924 8(3) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xn |
| Risk statements (R) | 11-14-19-36/37-40 |
| Safety statements (S) | 16-26-36/37 |
| Supplemental hazards | May form explosive peroxides. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Cyanobenzylzinc bromide solution used for?
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4-Cyanobenzylzinc bromide solution is primarily used as an organozinc reagent in organic synthesis, particularly for cross-coupling reactions to form carbon-carbon bonds and in the synthesis of pharmaceutical intermediates and fine chemicals.
What is the CAS number and formula for 4-Cyanobenzylzinc bromide solution?
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The CAS number is 135579-87-2 and the linear formula is NCC<sub>6</sub>H<sub>4</sub>CH<sub>2</sub>ZnBr.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Cyanobenzylzinc bromide solution at a concentration of 0.5 M in THF. TSS does not represent this product as USP, BP, or EP grade; it is suitable for research and technical applications.
How should 4-Cyanobenzylzinc bromide solution be handled safely?
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This product is highly flammable (H225) and may form explosive peroxides. It can cause skin and eye irritation (H319) and respiratory irritation (H335), and is suspected of causing cancer (H351). Handle with appropriate personal protective equipment in a well-ventilated area, away from ignition sources, and store refrigerated at 2-8°C.
How is 4-Cyanobenzylzinc bromide solution shipped and exported?
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4-Cyanobenzylzinc bromide solution is shipped and exported under UN 2924, Hazard Class 8 (3), Packing Group II, reflecting its hazardous nature. TSS adheres to all relevant shipping and export regulations.
How can I request a sample or quote?
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To request a sample or a quotation for 4-Cyanobenzylzinc bromide solution, please contact our sales team through the website or by calling our office. We will be happy to assist you.
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