4-(Chlorosulfonyl)benzoic acid
4-(Chlorosulfonyl)benzoic acid (CAS: 10130-89-9) is a reactive organic compound with the linear formula ClSO2C6H4CO2H and a molecular weight of 220.63 g/mol. This white to off-white solid serves as a valuable building block in chemical synthesis, particularly in the preparation of specialized polymers and complex organic molecules. Its sulfonyl chloride and carboxylic acid functionalities allow for diverse chemical transformations.

Preparation of Polymer-Supported Catalysts
4-(Chlorosulfonyl)benzoic acid has been utilised in the synthesis of polymer-bound transfer hydrogenation catalysts, facilitating heterogeneous catalysis applications.
Synthesis of Organic Molecules
It serves as a key intermediate in the preparation of various organic compounds, including biologically relevant molecules such as 4-(carboxymethyl-sulfamoyl)-benzoyladenosine.
Sulfonation Reagent
The compound acts as an effective reagent for the sulfonation of cyclodextrins, a process important in modifying carbohydrate structures for various applications.
| Molecular weight | 220.63 |
|---|---|
| Linear formula | ClSO2C6H4CO2H |
| Assay | 96% |
| Application | 4-(Chlorosulfonyl)benzoic acid was used in the preparation of polymer bound transfer hydrogenation catalyst1 and 4-(carboxymethyl-sulfamoyl)-benzoyladenosine2. It was also used as a reagent in the sulfonation of γ-cyclodextrin3. |
| Melting point | 233-235 °C(lit.) |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 3261 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-(Chlorosulfonyl)benzoic acid used for?
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4-(Chlorosulfonyl)benzoic acid is primarily used as a building block in chemical synthesis, including the preparation of polymer-bound catalysts, complex organic molecules, and for sulfonation reactions.
What is the CAS number and formula for 4-(Chlorosulfonyl)benzoic acid?
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The CAS number is 10130-89-9 and the linear formula is ClSO2C6H4CO2H.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-(Chlorosulfonyl)benzoic acid with an assay of 96%. We do not represent this product as USP, BP, or EP grade.
How should 4-(Chlorosulfonyl)benzoic acid be handled safely?
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4-(Chlorosulfonyl)benzoic acid causes severe skin burns and eye damage (H314). Handle with appropriate personal protective equipment, including eyeshields, face shields, gloves, and a suitable respirator. Ensure adequate ventilation.
Is 4-(Chlorosulfonyl)benzoic acid available for export?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 4-(Chlorosulfonyl)benzoic acid.
How can I request a quote or sample?
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Please contact our sales team directly through our website or by phone to request a quote or sample of 4-(Chlorosulfonyl)benzoic acid.
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