4′-Chlorodiazepam
4′-Chlorodiazepam (CAS: 14439-61-3) is a chemical compound with the formula C16H12Cl2N2O and a molecular weight of 319.19 g/mol. This substance serves as a peripheral benzodiazepine ligand, valuable in research for differentiating between central-type and peripheral-type benzodiazepine receptors. Its specific applications are primarily within neurobiological and pharmacological research settings.
- IUPAC
- 7-Chloro-5-(4-chlorophenyl)-1,3-dihydro-1-methyl-2H-1,4-benzodiazepin-2-one,Ro 5-4864,Ro5-4864
- Synonyms
- 7-Chloro-5-(4-chlorophenyl)-1,3-dihydro-1-methyl-2H-1,4-benzodiazepin-2-oneRo 5-4864Ro5-4864
Pharmacological Research
4′-Chlorodiazepam is utilized as a research tool to investigate the function and distribution of benzodiazepine receptors, particularly in distinguishing between central and peripheral subtypes. This aids in understanding their roles in various biological processes.
Neurobiology Studies
As a selective ligand for peripheral benzodiazepine receptors (TSPO), this compound facilitates studies into neuroinflammation, mitochondrial function, and cellular stress responses within the nervous system.
Ligand Binding Assays
It is employed in in vitro assays to characterize receptor binding affinities and kinetics, contributing to the development of new therapeutic agents targeting specific benzodiazepine receptor populations.
| Molecular weight | 319.19 |
|---|---|
| Empirical formula | C16H12Cl2N2O |
| Assay | ≥98% (TLC) |
| Solubility | 2-hydroxypropyl-β-cyclodextrin: insolubleH2O: insoluble |
| Application | Peripheral benzodiazepine ligand useful in distinguishing central-type from peripheral-type benzodiazepine receptors. |
Hazard statements
- H302Harmful if swallowed
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
| Safety statements (S) | 22-24/25 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Drug Control | regulated under CDSA - not available from Canada |
|---|---|
| Gene Information | rat ... Tspo(24230) |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4′-Chlorodiazepam used for?
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4′-Chlorodiazepam is primarily used as a peripheral benzodiazepine ligand in research settings to distinguish between central-type and peripheral-type benzodiazepine receptors, aiding studies in pharmacology and neurobiology.
What is the CAS number and molecular formula for 4′-Chlorodiazepam?
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The CAS number for 4′-Chlorodiazepam is 14439-61-3, and its molecular formula is C16H12Cl2N2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4′-Chlorodiazepam with a purity of ≥98% (TLC). This product is supplied for research purposes and TSS does not represent it as USP, BP, or EP grade.
What are the safety considerations when handling 4′-Chlorodiazepam?
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4′-Chlorodiazepam is classified with a GHS07 symbol and a Warning signal word, with hazard statement H302 (Harmful if swallowed). Appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves, should be used when handling this compound. Avoid inhalation and contact with skin and eyes.
Is 4′-Chlorodiazepam a controlled substance?
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Yes, 4′-Chlorodiazepam is regulated under the Controlled Drugs and Substances Act (CDSA) and is not available from Canada.
How are chemicals like 4′-Chlorodiazepam packed, shipped, and exported?
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Tech Serve Solutions adheres to stringent packaging, shipping, and export regulations for all chemicals, including 4′-Chlorodiazepam, ensuring compliance with international standards and customer requirements.
How can I request a sample or quote for 4′-Chlorodiazepam?
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To request a sample or a quote for 4′-Chlorodiazepam, please contact our sales department through the website or by telephone.
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