4-Chlorocinnamonitrile, mixture of cis and trans
4-Chlorocinnamonitrile (CAS: 28446-72-2) is an organic compound with the molecular formula ClC<sub>6</sub>H<sub>4</sub>CH=CHCN and a molecular weight of 163.60 g/mol. This chemical, existing as a mixture of cis and trans isomers, serves as a valuable building block in organic synthesis. It is particularly useful in the preparation of complex molecules and in studies comparing the reactivity of isomeric compounds.
- Synonyms
- ClC6H4CH=CHCN
Synthesis of Organic Intermediates
4-Chlorocinnamonitrile is employed in the synthesis of various organic intermediates, such as ethyl-1-(4-chlorophenyl)-2-cyanoethyl(diethoxymethyl)phosphinate. Its structure allows for diverse chemical transformations.
Polymerization Studies
This compound has been utilised in research to compare the radical and copolymerization abilities of geometrical isomers of cinnamonitriles. This aids in understanding structure-activity relationships in polymer science.
Research and Development
As a functionalised nitrile, 4-Chlorocinnamonitrile is a useful reagent in academic and industrial research laboratories for exploring new synthetic routes and novel compounds.
| Molecular weight | 163.60 |
|---|---|
| Linear formula | ClC6H4CH=CHCN |
| Assay | 98% |
| Application | 4-Chlorocinnamonitrile was used in the synthesis of ethyl-1-(4-chlorophenyl)-2-cyanoethyl(diethoxymethyl)phosphinate1. It was used to compare the radical and homocopolymerization ability of geometrical isomers of cinnamonitriles2. |
| Melting point | 55-70 °C(lit.) |
Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Chlorocinnamonitrile used for?
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4-Chlorocinnamonitrile is used as a building block in chemical synthesis, including the preparation of organic intermediates and in studies of polymerization.
What is the CAS number and molecular formula for 4-Chlorocinnamonitrile?
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The CAS number is 28446-72-2, and the linear formula is ClC<sub>6</sub>H<sub>4</sub>CH=CHCN.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Chlorocinnamonitrile with an assay of 98%. We do not represent this product as USP, BP, EP, or any other pharmacopoeial grade.
What are the primary safety concerns when handling 4-Chlorocinnamonitrile?
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4-Chlorocinnamonitrile is harmful if swallowed, in contact with skin, or if inhaled. It also causes skin irritation, serious eye irritation, and respiratory irritation. Appropriate personal protective equipment, including dust mask type N95, eyeshields, and gloves, should be used.
How is 4-Chlorocinnamonitrile packed and shipped?
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Tech Serve Solutions provides 4-Chlorocinnamonitrile in suitable packaging for safe transport and export worldwide. Specific packaging details can be provided upon request.
How can I request a sample or a quote for 4-Chlorocinnamonitrile?
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To request a sample or a quote, please contact our sales team through the website or by phone, providing the product name and CAS number (28446-72-2).
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