4-Chlorobenzylsulfonyl chloride
4-Chlorobenzylsulfonyl chloride (CAS: 6966-45-6; Formula: ClC6H4CH2SO2Cl) is a sulfonyl halide compound with a molecular weight of 225.09 g/mol. It serves as a valuable building block in organic synthesis. This reactive intermediate is primarily utilised in chemical synthesis for the introduction of the 4-chlorobenzylsulfonyl moiety into various organic structures, contributing to the development of complex molecules.
- IUPAC
- (4-Chlorophenyl)methanesulfonyl chloride,4-Chlorobenzenemethanesulfonyl chloride,p-Chloro-α-toluenesulfonyl chloride
- Synonyms
- (4-Chlorophenyl)methanesulfonyl chloride4-Chlorobenzenemethanesulfonyl chloridep-Chloro-α-toluenesulfonyl chloride

Organic Synthesis Intermediate
Utilised as a key reagent in the synthesis of diverse organic compounds. It facilitates the introduction of the 4-chlorobenzylsulfonyl group, enabling the construction of complex molecular architectures.
Pharmaceutical Research
Serves as a building block in the research and development of novel pharmaceutical agents. Its structure can be incorporated into molecules investigated for therapeutic potential.
Material Science
May be employed in the development of specialised materials where the incorporation of sulfur and chlorine functionalities is desired for specific properties.
| Molecular weight | 225.09 |
|---|---|
| Linear formula | ClC6H4CH2SO2Cl |
| Assay | 97% |
| Melting point | 93-97 °C |


Hazard statements
- H302Harmful if swallowed
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 3261 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 22-34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Chlorobenzylsulfonyl chloride used for?
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4-Chlorobenzylsulfonyl chloride is used as a building block and intermediate in organic synthesis, particularly for introducing the 4-chlorobenzylsulfonyl group into other molecules for research and development in areas such as pharmaceutical and material science.
What is the CAS number and chemical formula for 4-Chlorobenzylsulfonyl chloride?
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The CAS number for 4-Chlorobenzylsulfonyl chloride is 6966-45-6, and its chemical formula is ClC6H4CH2SO2Cl.
What grade and purity does Tech Serve Solutions supply for 4-Chlorobenzylsulfonyl chloride?
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Tech Serve Solutions supplies 4-Chlorobenzylsulfonyl chloride with an assay of 97%. We do not represent this product as USP, BP, or EP grade; it is suitable for technical and research applications.
How should 4-Chlorobenzylsulfonyl chloride be handled?
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4-Chlorobenzylsulfonyl chloride is classified as Danger, with hazards H302 (Harmful if swallowed) and H314 (Causes severe skin burns and eye damage). Appropriate personal protective equipment, including eyeshields, face shields, gloves, and respiratory protection (type N100 or P3 filters), must be used. Handle only in a well-ventilated area and seek immediate medical attention if exposed.
How is 4-Chlorobenzylsulfonyl chloride packed and exported?
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4-Chlorobenzylsulfonyl chloride is shipped as UN 3261, Class 8, Packing Group II, adhering to international regulations for hazardous material transport. Tech Serve Solutions is a specialist global supplier and exporter.
How can I request a quote or sample of 4-Chlorobenzylsulfonyl chloride?
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To request a quote or a sample of 4-Chlorobenzylsulfonyl chloride, please contact the Tech Serve Solutions sales team through our website or by phone.
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