4-Chloro-3-nitrobenzoyl chloride
4-Chloro-3-nitrobenzoyl chloride (CAS 38818-50-7) is a reactive organic compound with the linear formula ClC₆H₃(NO₂)COCl and a molecular weight of 220.01. As an acid halide, it serves as a key intermediate and building block in organic synthesis, particularly for introducing the 4-chloro-3-nitrobenzoyl moiety into larger molecules. Its utility spans various chemical manufacturing processes, contributing to the development of diverse organic compounds.

Organic Synthesis Intermediate
4-Chloro-3-nitrobenzoyl chloride is extensively used as an intermediate in the synthesis of complex organic molecules. Its reactive acid chloride group readily participates in acylation reactions, enabling the formation of esters, amides, and other derivatives.
Pharmaceutical Building Block
This compound acts as a crucial building block in the development of pharmaceutical agents. It can be incorporated into the synthetic routes of active pharmaceutical ingredients (APIs) and their precursors.
Agrochemical Synthesis
The unique structure of 4-chloro-3-nitrobenzoyl chloride makes it valuable in the synthesis of agrochemicals. It can be employed in the creation of pesticides, herbicides, and other crop protection agents.
Material Science Research
In material science, this chemical can be utilized for modifying polymers or synthesizing novel materials with specific electronic or optical properties, leveraging its functional groups for tailored applications.
| Molecular weight | 220.01 |
|---|---|
| Linear formula | ClC6H3(NO2)COCl |
| Assay | 98% |
| Melting point | 47-54 °C(lit.) |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 3261 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-27-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Chloro-3-nitrobenzoyl chloride used for?
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4-Chloro-3-nitrobenzoyl chloride is primarily used as an intermediate and building block in organic synthesis, including the preparation of pharmaceuticals, agrochemicals, and potentially in material science research.
What are the CAS number and formula for 4-Chloro-3-nitrobenzoyl chloride?
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The CAS number is 38818-50-7, and its linear formula is ClC₆H₃(NO₂)COCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Chloro-3-nitrobenzoyl chloride with an assay of 98%. We do not represent this product as meeting pharmacopoeia standards such as USP, BP, or EP.
How should 4-Chloro-3-nitrobenzoyl chloride be handled safely?
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4-Chloro-3-nitrobenzoyl chloride is a Danger hazard (GHS05, H314) that causes severe skin burns and eye damage. Appropriate personal protective equipment, including eyeshields, face shields, gloves, and respiratory protection (type N100 or P3), is essential. Handle only in a well-ventilated area.
Is this product suitable for export?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 4-Chloro-3-nitrobenzoyl chloride (UN 3261, 8/PGII).
How can I request a sample or quote?
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To request a sample or a quote for 4-Chloro-3-nitrobenzoyl chloride, please contact our sales team through the website or by phone.
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