4-Chloro-2-pyridinecarbonitrile
4-Chloro-2-pyridinecarbonitrile (CAS: 19235-89-3), with the empirical formula C6H3ClN2 and a molecular weight of 138.55 g/mol, is a halogenated heterocyclic compound. It serves as a valuable building block in chemical synthesis, particularly noted for its application as a substrate in preparing chiral dialkylaminopyridines via biocatalysis. This pyridine derivative is supplied by Tech Serve Solutions with an assay of 97%.
- IUPAC
- 2-Cyano-4-chloropyridine,4-Chloro-2-cyanopyridine,4-Chloropicolinonitrile
- Synonyms
- 2-Cyano-4-chloropyridine4-Chloro-2-cyanopyridine4-Chloropicolinonitrile

Biocatalytic Synthesis of Chiral Pyridines
This compound functions as a key substrate for biocatalytic transformations. It is specifically employed in the preparation of chiral dialkylaminopyridines that feature a C-2 hydroxyalkyl group.
Heterocyclic Building Block
As a halogenated pyridine derivative, 4-Chloro-2-pyridinecarbonitrile is a versatile building block for the synthesis of more complex heterocyclic structures in organic chemistry research and development.
Asymmetric Synthesis
Its structure makes it suitable for use in asymmetric synthesis, enabling the creation of stereochemically defined molecules, which is crucial in pharmaceutical and fine chemical development.
| Molecular weight | 138.55 |
|---|---|
| Empirical formula | C6H3ClN2 |
| Assay | 97% |
| Application | Substrate used to prepare chiral dialkylaminopyridines bearing a C-2 hydroxyalkyl group via biocatalysis.1 |
| Melting point | 81-85 °C |


Hazard statements
- H301Toxic if swallowed
- H318Causes serious eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-41 |
| Safety statements (S) | 26-39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Chloro-2-pyridinecarbonitrile used for?
+
4-Chloro-2-pyridinecarbonitrile (CAS: 19235-89-3) is primarily used as a substrate in biocatalysis for the preparation of chiral dialkylaminopyridines. It also functions as a versatile building block in organic synthesis, particularly in asymmetric synthesis and the development of heterocyclic compounds.
What are the CAS number and formula for 4-Chloro-2-pyridinecarbonitrile?
+
The CAS number for 4-Chloro-2-pyridinecarbonitrile is 19235-89-3, and its empirical formula is C6H3ClN2.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 4-Chloro-2-pyridinecarbonitrile with an assay of 97%. TSS does not represent this product as USP, BP, EP, or any pharmacopoeia grade unless explicitly stated in the product data.
How should 4-Chloro-2-pyridinecarbonitrile be handled safely?
+
4-Chloro-2-pyridinecarbonitrile is classified as Danger (GHS05, GHS06) with hazards including H301 (Toxic if swallowed) and H318 (Causes serious eye damage). Handle with appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, face shields, and gloves. Ensure adequate ventilation and follow precautionary statements P280, P301 + P310, and P305 + P351 + P338.
Can Tech Serve Solutions export this chemical?
+
Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 4-Chloro-2-pyridinecarbonitrile.
How can I request a quote or sample for 4-Chloro-2-pyridinecarbonitrile?
+
Please contact our sales team via the website or directly to request a quote or sample for 4-Chloro-2-pyridinecarbonitrile (CAS: 19235-89-3).
▶ Related products

1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis

1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis