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4-Chloro-2-fluorotoluene

CAS 452-75-5CH3C6H3(Cl)FChemical Synthesis

4-Chloro-2-fluorotoluene (CAS: 452-75-5) is a halogenated aromatic hydrocarbon with the molecular formula C7H6ClF and a molecular weight of 144.57 g/mol. Supplied by Tech Serve Solutions with a minimum purity of 99%, this compound serves as a valuable building block in organic synthesis. It is primarily utilised in chemical research and the preparation of more complex organic molecules, particularly in the field of fine chemicals and intermediates.

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4-Chloro-2-fluorotoluene (CH3C6H3(Cl)F) — chemical structure, CAS 452-75-5; Chemistry, fine chemical supplied by Tech Serve Solutions
ArylBuilding BlocksChemical SynthesisFluorinated Building BlocksHalogenated HydrocarbonsOrganic Building Blocks
01 /Applications

Organic Synthesis Intermediate

4-Chloro-2-fluorotoluene is employed as a key intermediate in the synthesis of various organic compounds. Its specific structure allows for targeted functionalization in multi-step reaction pathways.

Preparation of Benzyl Bromides

This compound has been documented in the preparation of 4-chloro-2-fluoro-benzylbromide, a useful reagent in further organic transformations.

Building Block for Fluorinated Compounds

As a fluorinated aryl compound, it functions as a critical building block for introducing fluorine into more complex molecular structures, relevant in pharmaceutical and agrochemical research.

02 /Properties
Molecular weight144.57
Linear formulaCH3C6H3(Cl)F
Assay≥99%
Boiling point158 °C/743 mmHg(lit.)
Density1.186 g/mL at 25 °C(lit.)
Refractive indexn20/D 1.498(lit.)
Application4-Chloro-2-fluorotoluene has been used in the preparation of 4-chloro-2-fluoro-benzylbromide1.
03 /Safety & handling
GHS hazard pictogram: Flammable (GHS02)
Flammable
GHS hazard pictogram: Harmful / irritant (GHS07)
Harmful / irritant
Warning

Hazard statements

  • H226Flammable liquid and vapour
  • H315Causes skin irritation
  • H319Causes serious eye irritation
  • H335May cause respiratory irritation

Precautionary statements

  • P261Avoid breathing dust, fume, gas or vapours
  • P305IF IN EYES
Protective equipmentEyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Flash point51 °C / 123.8 °F
Transport (UN / ADR)UN 1993C 3 / PGIII
Water hazard class (WGK, DE)3
Hazard codes (EU)Xi
Risk statements (R)10-36/37/38
Safety statements (S)16-26-36/37/39

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
452-75-5
MDL number
MFCD00000571
PubChem substance
24854886
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 4-Chloro-2-fluorotoluene primarily used for?

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4-Chloro-2-fluorotoluene is primarily used as an intermediate and building block in organic synthesis, including the preparation of compounds like 4-chloro-2-fluoro-benzylbromide.

What is the CAS number and formula for 4-Chloro-2-fluorotoluene?

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The CAS number for 4-Chloro-2-fluorotoluene is 452-75-5, and its molecular formula is CH3C6H3(Cl)F.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies 4-Chloro-2-fluorotoluene with a minimum assay of 99%. We do not represent this product as USP, BP, or EP grade.

What are the safety considerations when handling 4-Chloro-2-fluorotoluene?

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4-Chloro-2-fluorotoluene is classified as flammable and an irritant. It requires careful handling in a well-ventilated area, wearing appropriate personal protective equipment including eyeshields, gloves, and respiratory protection, and avoiding ignition sources. Refer to the Safety Data Sheet for comprehensive guidance.

How is 4-Chloro-2-fluorotoluene packed, shipped, and exported?

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4-Chloro-2-fluorotoluene is carefully packed according to international shipping regulations for hazardous materials. Tech Serve Solutions is experienced in global export of chemicals.

How can I request a quote or sample for 4-Chloro-2-fluorotoluene?

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To request a quote or a sample, please contact our sales department via the website or direct email, providing your specific requirements.

Need 4-Chloro-2-fluorotoluene in a specific grade or volume?