4-Chloro-2-fluorotoluene
4-Chloro-2-fluorotoluene (CAS: 452-75-5) is a halogenated aromatic hydrocarbon with the molecular formula C7H6ClF and a molecular weight of 144.57 g/mol. Supplied by Tech Serve Solutions with a minimum purity of 99%, this compound serves as a valuable building block in organic synthesis. It is primarily utilised in chemical research and the preparation of more complex organic molecules, particularly in the field of fine chemicals and intermediates.

Organic Synthesis Intermediate
4-Chloro-2-fluorotoluene is employed as a key intermediate in the synthesis of various organic compounds. Its specific structure allows for targeted functionalization in multi-step reaction pathways.
Preparation of Benzyl Bromides
This compound has been documented in the preparation of 4-chloro-2-fluoro-benzylbromide, a useful reagent in further organic transformations.
Building Block for Fluorinated Compounds
As a fluorinated aryl compound, it functions as a critical building block for introducing fluorine into more complex molecular structures, relevant in pharmaceutical and agrochemical research.
| Molecular weight | 144.57 |
|---|---|
| Linear formula | CH3C6H3(Cl)F |
| Assay | ≥99% |
| Boiling point | 158 °C/743 mmHg(lit.) |
| Density | 1.186 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.498(lit.) |
| Application | 4-Chloro-2-fluorotoluene has been used in the preparation of 4-chloro-2-fluoro-benzylbromide1. |


Hazard statements
- H226Flammable liquid and vapour
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 51 °C / 123.8 °F |
| Transport (UN / ADR) | UN 1993C 3 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 10-36/37/38 |
| Safety statements (S) | 16-26-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Chloro-2-fluorotoluene primarily used for?
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4-Chloro-2-fluorotoluene is primarily used as an intermediate and building block in organic synthesis, including the preparation of compounds like 4-chloro-2-fluoro-benzylbromide.
What is the CAS number and formula for 4-Chloro-2-fluorotoluene?
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The CAS number for 4-Chloro-2-fluorotoluene is 452-75-5, and its molecular formula is CH3C6H3(Cl)F.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Chloro-2-fluorotoluene with a minimum assay of 99%. We do not represent this product as USP, BP, or EP grade.
What are the safety considerations when handling 4-Chloro-2-fluorotoluene?
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4-Chloro-2-fluorotoluene is classified as flammable and an irritant. It requires careful handling in a well-ventilated area, wearing appropriate personal protective equipment including eyeshields, gloves, and respiratory protection, and avoiding ignition sources. Refer to the Safety Data Sheet for comprehensive guidance.
How is 4-Chloro-2-fluorotoluene packed, shipped, and exported?
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4-Chloro-2-fluorotoluene is carefully packed according to international shipping regulations for hazardous materials. Tech Serve Solutions is experienced in global export of chemicals.
How can I request a quote or sample for 4-Chloro-2-fluorotoluene?
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To request a quote or a sample, please contact our sales department via the website or direct email, providing your specific requirements.
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