4-Chloro-2,5-difluorobenzoic acid
4-Chloro-2,5-difluorobenzoic acid (CAS: 132794-07-1), a fluorinated aromatic carboxylic acid with a molecular weight of 192.55 g/mol, serves as a key building block in organic synthesis. Its structure, featuring a chlorine atom and two fluorine atoms on a benzoic acid core, allows for diverse chemical transformations. This compound is primarily utilised in the research and development of new materials and active pharmaceutical ingredients.
- Synonyms
- ClC6H2(F)2CO2H

Pharmaceutical Intermediate
This compound functions as a crucial intermediate in the synthesis of complex pharmaceutical molecules. Its fluorinated aromatic structure is often incorporated into drug candidates to modulate properties like metabolic stability and binding affinity.
Agrochemical Synthesis
4-Chloro-2,5-difluorobenzoic acid can be employed in the development of novel agrochemicals. The presence of halogens can influence the biological activity and environmental persistence of pesticide and herbicide formulations.
Material Science
The unique electronic and structural properties conferred by the fluorine and chlorine substituents make this acid a valuable component in the synthesis of advanced materials, potentially for use in electronics or specialty polymers.
Organic Synthesis Building Block
As a versatile building block, it is used in academic and industrial research for creating a wide array of novel organic compounds through various chemical reactions.
| Molecular weight | 192.55 |
|---|---|
| Linear formula | ClC6H2(F)2CO2H |
| Assay | 98% |
| Melting point | 154-157 °C(lit.) |

Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Chloro-2,5-difluorobenzoic acid used for?
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4-Chloro-2,5-difluorobenzoic acid is primarily used as a building block in organic synthesis for the development of pharmaceutical intermediates, agrochemicals, and advanced materials.
What is the CAS number and molecular formula for 4-Chloro-2,5-difluorobenzoic acid?
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The CAS number is 132794-07-1. The linear formula is ClC6H2(F)2CO2H.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with a minimum assay of 98%. We do not represent it as USP, BP, EP, or other pharmacopoeia grades unless explicitly stated.
How should 4-Chloro-2,5-difluorobenzoic acid be handled?
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Handle with appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves. Avoid breathing dust, and ensure adequate ventilation. It is a Warning substance with hazards including H302, H312, H315, H319, H332, and H335.
How is 4-Chloro-2,5-difluorobenzoic acid shipped and exported?
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Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 4-Chloro-2,5-difluorobenzoic acid. Packaging and shipping comply with international regulations for hazardous materials.
How can I request a quote or sample?
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Please contact our sales team via the website or telephone to request a quotation or a sample of 4-Chloro-2,5-difluorobenzoic acid.
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