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4-Chloro-1-butanol

CAS 928-51-8HO(CH2)4ClChemical Synthesis

4-Chloro-1-butanol (CAS: 928-51-8), with the chemical formula HO(CH2)4Cl and a molecular weight of 108.57 g/mol, is a valuable organic building block. This halogenated alcohol serves as a versatile intermediate in various chemical synthesis processes. Its structure, featuring both a hydroxyl and a chloro functional group, allows for diverse reactivity, making it a useful reagent in the preparation of more complex organic molecules. Tech Serve Solutions offers this compound for research and industrial applications.

IUPAC
Tetramethylene chlorohydrin
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4-Chloro-1-butanol (HO(CH2)4Cl) — chemical structure, CAS 928-51-8; Chemistry, fine chemical supplied by Tech Serve Solutions
AlcoholsBuilding BlocksC2 to C6Chemical SynthesisOrganic Building BlocksOxygen Compounds More...
01 /Applications

Organic Synthesis Intermediate

4-Chloro-1-butanol is employed as a key intermediate in the synthesis of diverse organic compounds. Its bifunctional nature allows for selective reactions at either the alcohol or alkyl halide site, facilitating the construction of various molecular architectures.

Pharmaceutical Precursor

This compound can serve as a starting material or intermediate in the multi-step synthesis of pharmaceutical agents. Its chloro and hydroxyl functionalities are amenable to transformations required for building complex drug molecules.

Building Block for Heterocycles

The structure of 4-Chloro-1-butanol makes it suitable for cyclization reactions, contributing to the formation of various heterocyclic compounds, which are prevalent in medicinal chemistry and materials science.

02 /Properties
Molecular weight108.57
Linear formulaHO(CH2)4Cl
Assay≥90% (GC)
Gradetechnical
Boiling point84-85 °C/16 mmHg(lit.)
Density1.088 g/mL at 25 °C(lit.)
Refractive indexn20/D 1.453(lit.)n20/D 1.453
Storage temperature2-8°C
Impurities tested≤4% free HCl
03 /Safety & handling
GHS hazard pictogram: Flammable (GHS02)
Flammable
GHS hazard pictogram: Harmful / irritant (GHS07)
Harmful / irritant
Warning

Hazard statements

  • H226Flammable liquid and vapour
  • H302Harmful if swallowed
  • H315Causes skin irritation
  • H319Causes serious eye irritation
  • H335May cause respiratory irritation

Precautionary statements

  • P261Avoid breathing dust, fume, gas or vapours
  • P305IF IN EYES
Protective equipmentFaceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Flash point36 °C / 96.8 °F
Transport (UN / ADR)UN 2924 8(3) / PGIII
Water hazard class (WGK, DE)3
Hazard codes (EU)Xn
Risk statements (R)10-22-36/37/38
Safety statements (S)26

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
928-51-8
MDL number
MFCD00002967
Beilstein registry
1731408
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 4-Chloro-1-butanol used for?

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4-Chloro-1-butanol is primarily used as an intermediate in organic synthesis, including the preparation of pharmaceutical agents and heterocyclic compounds. It is a versatile building block in chemical research and development.

What are the CAS number and chemical formula for 4-Chloro-1-butanol?

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The CAS number for 4-Chloro-1-butanol is 928-51-8, and its chemical formula is HO(CH2)4Cl.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies 4-Chloro-1-butanol in a technical grade with an assay of ≥90% (GC). This product is not represented as USP, BP, or EP grade.

How should 4-Chloro-1-butanol be handled safely?

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4-Chloro-1-butanol is a flammable liquid and vapour (H226), harmful if swallowed (H302), and causes skin (H315), serious eye (H319), and respiratory irritation (H335). Handle with appropriate personal protective equipment, including gloves, eye protection, and respiratory protection, in a well-ventilated area. Store at 2-8°C.

Is 4-Chloro-1-butanol a controlled substance?

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Based on the provided data, 4-Chloro-1-butanol is not indicated as a controlled substance.

How is 4-Chloro-1-butanol packed and exported?

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Tech Serve Solutions, as a specialist global supplier and exporter, ensures appropriate packaging for 4-Chloro-1-butanol in compliance with international shipping regulations for chemical products.

How can I request a sample or quote for 4-Chloro-1-butanol?

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To request a sample or a quote for 4-Chloro-1-butanol, please contact our sales department through the website or by phone. Our team will be pleased to assist you with your requirements.

Need 4-Chloro-1-butanol in a specific grade or volume?