4-Bromo-2-fluorobenzenesulfonyl chloride
4-Bromo-2-fluorobenzenesulfonyl chloride (CAS: 216159-03-4), with the molecular formula BrC6H3(F)SO2Cl and a molecular weight of 273.51 g/mol, is a specialised organic intermediate. It serves as a valuable building block in organic synthesis, particularly for introducing the 4-bromo-2-fluorobenzenesulfonyl group into target molecules. Its chemical structure lends itself to applications in the development of novel compounds within pharmaceutical research and material science.

Organic Synthesis Intermediate
Utilised as a key reactant for incorporating the 4-bromo-2-fluorobenzenesulfonyl moiety in complex organic molecule construction. This is crucial in multi-step synthesis pathways for advanced chemical entities.
Pharmaceutical Research
Acts as a building block for the synthesis of potential drug candidates. Its specific functional groups allow for targeted modifications in medicinal chemistry programmes aimed at developing new therapeutic agents.
Material Science
Can be employed in the development of new materials with specific electronic or physical properties. The fluorinated aryl sulfonyl chloride structure offers unique reactivity for material functionalisation.
| Molecular weight | 273.51 |
|---|---|
| Linear formula | BrC6H3(F)SO2Cl |
| Assay | 97% |
| Melting point | 63-66 °C(lit.) |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 3261 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 22-26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Bromo-2-fluorobenzenesulfonyl chloride used for?
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4-Bromo-2-fluorobenzenesulfonyl chloride (CAS: 216159-03-4) is primarily used as an intermediate and building block in organic synthesis, particularly in pharmaceutical research and material science for the construction of complex organic molecules.
What are the CAS number and formula for 4-Bromo-2-fluorobenzenesulfonyl chloride?
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The CAS number is 216159-03-4 and the linear formula is BrC6H3(F)SO2Cl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Bromo-2-fluorobenzenesulfonyl chloride with an assay of 97%. We do not represent this product as USP, BP, EP, or any other pharmacopoeial grade.
How should 4-Bromo-2-fluorobenzenesulfonyl chloride be handled safely?
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This compound causes severe skin burns and eye damage (H314). Handle with appropriate personal protective equipment, including eyeshields, face shields, and chemically resistant gloves. Ensure adequate ventilation or use a respirator. In case of contact, rinse immediately with plenty of water and seek medical advice.
How is 4-Bromo-2-fluorobenzenesulfonyl chloride packed, shipped, and exported?
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This compound is packed in compliance with transport regulations, such as UN 3261, Class 8, Packing Group II. Tech Serve Solutions, established in 1998, is an experienced global supplier and exporter of fine chemicals.
How can I request a sample or quote for 4-Bromo-2-fluorobenzenesulfonyl chloride?
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To request a sample or a quotation, please contact our sales team via the website or directly by phone. Our team will be pleased to assist you with your specific requirements.
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