4-Bromo-2,6-difluorophenylboronic acid
4-Bromo-2,6-difluorophenylboronic acid (CAS: 352535-81-0) is a key organoboron compound with the molecular formula C6H4BBrF2O2. Possessing a molar mass of 236.81 g/mol, this aryl boronic acid derivative serves as a valuable building block in organic synthesis. Its utility is primarily recognised in cross-coupling reactions and the construction of complex molecular architectures for research and development purposes in various chemical fields.
- Synonyms
- C6H4BBrF2O2

Organic Synthesis Intermediate
This compound functions as a crucial intermediate in the synthesis of more complex organic molecules. It is frequently employed in Suzuki-Miyaura cross-coupling reactions, enabling the formation of carbon-carbon bonds.
Pharmaceutical Research
It is utilized in the development of novel pharmaceutical candidates. The difluorophenylboronic acid moiety can be incorporated into drug discovery programs, exploring its potential biological activity.
Materials Science
The unique electronic and structural properties imparted by the fluorine and bromine substituents make it suitable for research in advanced materials. This includes its potential use in the synthesis of organic electronic materials.
| Molecular weight | 236.81 |
|---|---|
| Empirical formula | C6H4BBrF2O2 |
| Melting point | 155-160 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Bromo-2,6-difluorophenylboronic acid used for?
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4-Bromo-2,6-difluorophenylboronic acid is primarily used as an intermediate in organic synthesis, particularly in Suzuki-Miyaura cross-coupling reactions, and in pharmaceutical research and materials science.
What is the CAS number and formula for 4-Bromo-2,6-difluorophenylboronic acid?
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The CAS number is 352535-81-0 and the molecular formula is C6H4BBrF2O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical for research and development purposes. The specific grade and purity are available on the product's Certificate of Analysis. It is not supplied as USP, BP, EP, or pharmacopoeia grade.
How should 4-Bromo-2,6-difluorophenylboronic acid be handled?
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Handling requires appropriate safety measures, including the use of eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used. Please refer to the Safety Data Sheet (SDS) for comprehensive handling guidelines.
Is 4-Bromo-2,6-difluorophenylboronic acid a controlled substance?
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The provided data does not indicate that 4-Bromo-2,6-difluorophenylboronic acid is a controlled substance.
How is 4-Bromo-2,6-difluorophenylboronic acid packed, shipped, and exported?
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Tech Serve Solutions packages chemicals securely for safe transit and export in compliance with all relevant regulations. Specific packaging details depend on quantity and destination.
How can I request a sample or quote for 4-Bromo-2,6-difluorophenylboronic acid?
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Please contact our sales team via the website or by phone to request a sample or a quotation for 4-Bromo-2,6-difluorophenylboronic acid. Please provide your contact details and required quantity.
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