4-Benzyloxy-3-methoxybenzaldehyde
4-Benzyloxy-3-methoxybenzaldehyde (CAS 2426-87-1), with the molecular formula C15H14O3 and a molecular weight of 242.27 g/mol, is a valuable organic building block. This aldehyde derivative, also known as O-Benzylvanillin, is utilised in complex organic synthesis, including the preparation of pharmaceutical intermediates and biologically active compounds. Its structure offers versatile reactivity for chemists in research and development.
- IUPAC
- O-Benzylvanillin,Vanillin benzyl ether
- Synonyms
- O-BenzylvanillinVanillin benzyl ether

Synthesis of Complex Molecules
4-Benzyloxy-3-methoxybenzaldehyde served as a key intermediate in the synthesis of 1,2-bis(4-benzyloxy-3-methoxyphenyl)-3-hydroxy-propionic acid. This demonstrates its utility in constructing intricate molecular frameworks.
Enantioselective Synthesis
The compound was employed in the first enantioselective total synthesis of the neurotrophic agent (-)-talaumidin. This highlights its role in asymmetric synthesis pathways.
Organic Building Block
As a functionalised benzaldehyde, it is widely used as a versatile building block in various organic synthesis strategies for creating diverse chemical entities.
| Molecular weight | 242.27 |
|---|---|
| Linear formula | C6H5CH2OC6H3(OCH3)CHO |
| Assay | 98% |
| Application | 4-Benzyloxy-3-methoxybenzaldehyde was used in the synthesis of 1,2-bis(4-benzyloxy-3-methoxyphenyl)-3-hydroxy-propionic acid1. It was also used in first enantioselective total synthesis of a neurotrophic (-)-talaumidin2. |
| Melting point | 62-64 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Benzyloxy-3-methoxybenzaldehyde used for?
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4-Benzyloxy-3-methoxybenzaldehyde is used as a building block in organic synthesis, including the preparation of complex molecules and in enantioselective synthesis.
What are the CAS number and molecular formula?
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The CAS number is 2426-87-1 and the molecular formula is C15H14O3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Benzyloxy-3-methoxybenzaldehyde with an assay of 98%. This is a research or technical grade material, and TSS does not represent it as USP, BP, or EP grade.
What are the safety and handling precautions for this chemical?
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Users should wear eyeshields and gloves, and use a type N95 (US) or type P1 (EN143) respirator filter. The substance is classified under WGK Germany 3.
How is 4-Benzyloxy-3-methoxybenzaldehyde packed, shipped, and exported?
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Tech Serve Solutions, established in 1998, is a specialist global supplier and exporter of fine chemicals. Specific packaging and shipping details are available upon request.
How can I request a sample or quote?
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Please contact our sales team to request a sample or a quotation for 4-Benzyloxy-3-methoxybenzaldehyde.
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