4-Benzoylphenylboronic acid
4-Benzoylphenylboronic acid (CAS 268218-94-6) is an organoborane compound with the formula C6H5COC6H4B(OH)2 and a molecular weight of 226.04 g/mol. This substituted aryl boronic acid serves as a valuable building block in organic synthesis. Its primary applications involve its use as a reactant in palladium-catalyzed cross-coupling reactions, including the Suzuki coupling, and in the synthesis of complex organic molecules.
- IUPAC
- 4-(Phenylcarbonyl)phenylboronic acid
- Synonyms
- 4-(Phenylcarbonyl)phenylboronic acid
Suzuki Cross-Coupling Reactions
4-Benzoylphenylboronic acid is a key reactant in Suzuki-Miyaura cross-coupling reactions. This palladium-catalyzed process facilitates the formation of carbon-carbon bonds, enabling the synthesis of biaryl compounds and other complex organic structures.
Pd-Catalyzed Regioselective Cross-Coupling
This boronic acid participates in palladium-catalyzed regioselective cross-coupling reactions, offering a route to precisely functionalised aromatic systems crucial for advanced chemical synthesis.
Synthesis of Enterovirus Inhibitors
It has been employed as a precursor in the synthesis of 9-arylpurines, a novel class of compounds investigated for their potential as enterovirus inhibitors. This highlights its utility in medicinal chemistry research.
| Molecular weight | 226.04 |
|---|---|
| Linear formula | C6H5COC6H4B(OH)2 |
| Assay | ≥95% |
| Application | Reactant for:• Pd-catalyzed regioselective cross-coupling reactions1• Synthesis of 9-arylpurines as a novel class of Enterovirus inhibitors2• Suzuki cross-coupling3 |
| Melting point | 204-212 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Benzoylphenylboronic acid used for?
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4-Benzoylphenylboronic acid is used as a reactant in palladium-catalyzed cross-coupling reactions, such as the Suzuki coupling, and in the synthesis of specific organic molecules like 9-arylpurines with potential biological activity.
What is the CAS number and formula for 4-Benzoylphenylboronic acid?
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The CAS number for 4-Benzoylphenylboronic acid is 268218-94-6, and its chemical formula is C6H5COC6H4B(OH)2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Benzoylphenylboronic acid with a purity of ≥95%. We do not represent this product as meeting USP, BP, or EP pharmacopoeia standards; it is supplied for research and chemical synthesis purposes.
How should 4-Benzoylphenylboronic acid be handled safely?
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Handling requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used. The substance has a WGK rating of 3 in Germany, indicating it is hazardous to water.
How can I request a quote or sample for 4-Benzoylphenylboronic acid?
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To request a quote or sample of 4-Benzoylphenylboronic acid, please contact our sales team through the website or by phone. We export globally to meet diverse customer needs.
Is 4-Benzoylphenylboronic acid a controlled substance?
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The provided data does not indicate that 4-Benzoylphenylboronic acid is a controlled substance.
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