4-(Aminomethyl)indole
4-(Aminomethyl)indole (CAS 3468-18-6), with the molecular formula C9H10N2 and a molecular weight of 146.19 g/mol, is a heterocyclic organic compound. It serves as a key building block in chemical synthesis. Its primary applications lie in the preparation of complex molecules, including dopamine receptor antagonists and high-affinity ligands for voltage-gated calcium channels, contributing to advancements in medicinal chemistry research.
- IUPAC
- NSC 131886
Dopamine Receptor Antagonist Synthesis
This compound is utilised as a reactant in the synthesis of dopamine receptor antagonists. These antagonists are crucial in pharmacological research and the development of therapeutic agents targeting neurological disorders.
Ligand Development for Calcium Channels
4-(Aminomethyl)indole is employed in the preparation of high-affinity ligands. Specifically, these ligands target the α2δ subunit of voltage-gated calcium channels, which are important targets for pain and neurological disorder treatments.
Heterocyclic Building Block
As a versatile indole derivative, it functions as a fundamental building block in the construction of more complex heterocyclic structures for diverse chemical research and development purposes.
| Molecular weight | 146.19 |
|---|---|
| Empirical formula | C9H10N2 |
| Assay | 95% |
| Application | • Reactant for preparation of dopamine receptor antagonists1• Reactant for preparation of high-affinity ligands to α2δ subunit of voltage-gated calcium channels2 |
| Melting point | 130-135 °C |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H318Causes serious eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-37/38-41 |
| Safety statements (S) | 26-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-(Aminomethyl)indole used for?
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4-(Aminomethyl)indole (CAS 3468-18-6) is primarily used as a reactant in chemical synthesis, notably for preparing dopamine receptor antagonists and high-affinity ligands to the α2δ subunit of voltage-gated calcium channels.
What is the CAS number and molecular formula for 4-(Aminomethyl)indole?
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The CAS number for 4-(Aminomethyl)indole is 3468-18-6, and its molecular formula is C9H10N2.
What grade and purity does Tech Serve Solutions supply for 4-(Aminomethyl)indole?
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Tech Serve Solutions supplies 4-(Aminomethyl)indole with an assay of 95%. This product is supplied for research and development purposes and is not represented as USP, BP, EP, or any other pharmacopoeial grade.
How should 4-(Aminomethyl)indole be handled safely?
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4-(Aminomethyl)indole is classified as Danger. It is harmful if swallowed (H302), causes skin irritation (H315), causes serious eye damage (H318), and may cause respiratory irritation (H335). Always use appropriate personal protective equipment, including gloves, eye protection, and respiratory protection, and handle in a well-ventilated area. Consult the Safety Data Sheet (SDS) for detailed handling instructions.
Is 4-(Aminomethyl)indole a controlled substance?
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The provided data does not indicate that 4-(Aminomethyl)indole is a scheduled or controlled substance.
How is 4-(Aminomethyl)indole shipped and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals. 4-(Aminomethyl)indole is carefully packed to ensure safe transit and exported according to international regulations. Specific shipping and export details can be provided upon request.
How can I request a sample or quote for 4-(Aminomethyl)indole?
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To request a sample or obtain a quote for 4-(Aminomethyl)indole, please contact the Tech Serve Solutions sales team through our website or by phone, providing your specific requirements.
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