4-Amino-8-trifluoromethoxyquinoline
4-Amino-8-trifluoromethoxyquinoline (CAS: 874880-24-7, C10H7F3N2O) is a specialized heterocyclic building block with a molecular weight of 228.17 g/mol. This fluorinated quinoline derivative is primarily utilised in chemical synthesis and research applications, serving as a key intermediate for the development of novel compounds. Its unique structure makes it valuable for introducing specific functionalities into larger molecules, particularly in medicinal chemistry and materials science research.

Organic Synthesis Intermediate
Serves as a versatile building block in complex organic syntheses. It is used to construct more elaborate molecular architectures, often found in the discovery phases of new pharmaceuticals and agrochemicals.
Medicinal Chemistry Research
A valuable scaffold for developing drug candidates. The quinoline core, combined with trifluoromethoxy and amino substituents, offers unique electronic and steric properties for lead optimization in therapeutic research.
Materials Science Exploration
Can be employed in the synthesis of functional materials. Its fluorinated nature may impart specific properties relevant to areas such as organic electronics or advanced polymers.
| Molecular weight | 228.17 |
|---|---|
| Empirical formula | C10H7F3N2O |

Hazard statements
- H301Toxic if swallowed
- H319Causes serious eye irritation
Precautionary statements
- P301IF SWALLOWED
- P305IF IN EYES
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25-36 |
| Safety statements (S) | 26-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Amino-8-trifluoromethoxyquinoline used for?
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4-Amino-8-trifluoromethoxyquinoline (CAS: 874880-24-7) is primarily used as a building block in organic synthesis, particularly in medicinal chemistry research and the development of new materials. It is an intermediate for creating more complex fluorinated heterocyclic compounds.
What are the CAS number and formula for 4-Amino-8-trifluoromethoxyquinoline?
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The CAS number for 4-Amino-8-trifluoromethoxyquinoline is 874880-24-7, and its empirical formula is C10H7F3N2O.
What grade and purity does Tech Serve Solutions supply for 4-Amino-8-trifluoromethoxyquinoline?
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Tech Serve Solutions supplies this compound for research and development purposes. Specific grades and purities can be provided upon request; it is not supplied as USP, BP, EP, or any other pharmacopoeial grade.
What are the main hazards associated with 4-Amino-8-trifluoromethoxyquinoline?
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4-Amino-8-trifluoromethoxyquinoline is classified as Toxic if swallowed (H301) and causes serious eye irritation (H319). Appropriate safety precautions, including wearing protective equipment and ensuring good ventilation, are essential during handling.
How is 4-Amino-8-trifluoromethoxyquinoline packed and shipped?
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This chemical is packed and shipped according to international regulations for hazardous materials, including UN 2811 classification (Toxic solid, organic, n.o.s.). TSS ensures compliance for global export.
How can I request a quote or sample for 4-Amino-8-trifluoromethoxyquinoline?
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To request a quote or sample, please contact the Tech Serve Solutions sales team via our website or direct inquiry, providing your contact details and the required quantity.
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