4-Amino-2,3,5,6-tetrafluorobenzoic acid
4-Amino-2,3,5,6-tetrafluorobenzoic acid (CAS 944-43-4, H<sub>2</sub>NC<sub>6</sub>F<sub>4</sub>CO<sub>2</sub>H) is a fluorinated aromatic amino acid derivative with a molecular weight of 209.10 g/mol. This compound serves as a valuable building block in chemical synthesis, particularly in the development of novel peptides and in chemical biology research. Its unique fluorinated structure lends specific properties for advanced applications.
- Synonyms
- 6-tetrafluorobenzoic acid944-43-4H2NC6F4CO2H

Chemical Synthesis Intermediate
Utilised as a key intermediate in the synthesis of complex organic molecules. Its tetrafluorinated phenyl ring and amino acid functionality allow for diverse chemical transformations.
Peptide Chemistry
Incorporated into peptide chains to create unnatural amino acid derivatives. This can modify peptide structure, stability, and biological activity for research purposes.
Chemical Biology Research
Employed in studies exploring molecular interactions and biological pathways. The fluorinated moiety can serve as a probe or influence molecular recognition.
| Molecular weight | 209.10 |
|---|---|
| Linear formula | H2NC6F4CO2H |
| Assay | 99% |
| Melting point | 185-187 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Amino-2,3,5,6-tetrafluorobenzoic acid used for?
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This compound is primarily used as an intermediate in chemical synthesis, for applications in peptide chemistry, and in chemical biology research due to its unique fluorinated aromatic amino acid structure.
What are the CAS number and molecular formula?
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The CAS number is 944-43-4, and the molecular formula is H₂NC₆F₄CO₂H.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical with a purity of 99%. We do not represent this product as meeting USP, BP, or EP pharmacopoeia standards.
How should 4-Amino-2,3,5,6-tetrafluorobenzoic acid be handled?
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Handle with appropriate personal protective equipment including a dust mask (type N95 US recommended), eyeshields, and gloves. Avoid breathing dust. This compound is classified as an irritant to the skin, eyes, and respiratory tract.
Is this product available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, pharmaceutical intermediates, and laboratory reagents.
How can I request a quote or sample?
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Please contact our sales team via the website or direct email to request a quote or a sample for 4-Amino-2,3,5,6-tetrafluorobenzoic acid.
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