4-Acetylbenzenesulfonyl chloride
4-Acetylbenzenesulfonyl chloride (CAS: 1788-10-9), with the molecular formula C8H7ClO3S and a molecular weight of 218.66 g/mol, is a specialised organic building block. It is primarily utilised in chemical synthesis as a reactive intermediate. This compound offers a versatile functional group for introducing the 4-acetylbenzenesulfonyl moiety into various molecular structures.
- IUPAC
- Acetophenone-4-sulfonyl chloride

Organic Synthesis Intermediate
Serves as a key intermediate in the synthesis of complex organic molecules. Its sulfonyl chloride functionality readily reacts with nucleophiles, enabling the formation of sulfonamides and sulfonates.
Pharmaceutical Research and Development
Employed in the research and development of new pharmaceutical agents. It can be incorporated into potential drug candidates for various therapeutic areas.
Material Science
Used in the development of novel materials. The compound can be a precursor for functional polymers or specialised additives.
| Molecular weight | 218.66 |
|---|---|
| Empirical formula | C8H7ClO3S |
| Assay | ≥95.0% (AT) |
| Melting point | 84-87 °C |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 3261 8 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Acetylbenzenesulfonyl chloride used for?
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4-Acetylbenzenesulfonyl chloride (CAS: 1788-10-9) is primarily used as an intermediate in organic synthesis, particularly in pharmaceutical research and material science.
What are the CAS number and formula for 4-Acetylbenzenesulfonyl chloride?
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The CAS number for 4-Acetylbenzenesulfonyl chloride is 1788-10-9, and its molecular formula is C8H7ClO3S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Acetylbenzenesulfonyl chloride with an assay of ≥95.0% (AT). This is a technical/research grade, and TSS does not represent it as USP, BP, or EP grade.
How should 4-Acetylbenzenesulfonyl chloride be handled?
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4-Acetylbenzenesulfonyl chloride is classified as corrosive (H314) and requires stringent safety precautions. Handlers must wear appropriate personal protective equipment, including eyeshields, face shields, gloves, and respiratory protection (e.g., N100 or P3 filters), to prevent skin and eye damage and respiratory irritation.
Is 4-Acetylbenzenesulfonyl chloride available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 4-Acetylbenzenesulfonyl chloride, which can be shipped worldwide.
How can I request a quote or sample?
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To request a quote or a sample of 4-Acetylbenzenesulfonyl chloride, please contact our sales team through the website or by phone.
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