4,4′-(Hexafluoroisopropylidene)diphenol
4,4′-(Hexafluoroisopropylidene)diphenol (CAS: 1478-61-1), also known as Bisphenol AF, is a fluorinated bisphenol compound with the linear formula (CF₃)₂C(C₆H₄OH)₂ and a molecular weight of 336.23 g/mol. This white crystalline solid serves as a key monomer in the synthesis of advanced polymers. Its unique chemical structure imparts desirable properties such as enhanced thermal stability and chemical resistance to the resulting materials, making it valuable in specialised applications.
- IUPAC
- 2,2-Bis(4-hydroxyphenyl)hexafluoropropane,Bisphenol AF,Hexafluorobisphenol A
- Synonyms
- Bisphenol AFBisphenol AFHexafluorobisphenol A2,2-Bis(4-hydroxyphenyl)hexafluoropropane

Polymer Synthesis
Utilised as a monomer for the production of high-performance polymers, including polycarbonates, polyesters, and polyethers. These polymers exhibit superior thermal stability, chemical resistance, and optical properties.
Monomer for Specialty Resins
Serves as a building block for specialty resins and materials requiring enhanced performance characteristics. Its incorporation can improve dielectric properties and reduce flammability in formulated resins.
Materials Science Research
Employed in materials science research for the development of novel fluorinated polymers and composites. Its distinct structure allows for fine-tuning of material properties for advanced applications.
| Molecular weight | 336.23 |
|---|---|
| Linear formula | (CF3)2C(C6H4OH)2 |
| Assay | 97% |
| Melting point | 160-163 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4,4′-(Hexafluoroisopropylidene)diphenol primarily used for?
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4,4′-(Hexafluoroisopropylidene)diphenol is primarily used as a monomer in the synthesis of high-performance polymers, such as specialty polycarbonates, polyesters, and polyethers, which benefit from its imparted thermal stability and chemical resistance.
What are the CAS number and chemical formula for this compound?
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The CAS number for 4,4′-(Hexafluoroisopropylidene)diphenol is 1478-61-1, and its linear chemical formula is (CF₃)₂C(C₆H₄OH)₂.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4,4′-(Hexafluoroisopropylidene)diphenol with an assay of 97%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should 4,4′-(Hexafluoroisopropylidene)diphenol be handled safely?
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This compound is classified as a Warning. It may cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves, should be worn. Avoid breathing dust and ensure adequate ventilation. In case of eye contact, rinse cautiously with water for several minutes, removing contact lenses if present and easy to do (P305 + P351 + P338).
Is this product suitable for use in pharmaceutical applications?
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Based on the provided data, this product is supplied at a 97% assay and is not designated as USP, BP, or EP grade. Its applications are primarily in polymer science and materials. For pharmaceutical use, please consult specific regulatory documentation and required grades.
How is 4,4′-(Hexafluoroisopropylidene)diphenol packed and shipped?
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Tech Serve Solutions, as a global supplier and exporter, ensures appropriate packaging and shipping procedures are followed for chemicals. Please contact us directly for specific details regarding packaging options and international export capabilities for this product.
How can I request a sample or quote for 4,4′-(Hexafluoroisopropylidene)diphenol?
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To request a sample or a quotation, please visit the 'Contact Us' section of our website or use the 'Request Quote' functionality available on the product page. Our sales team will respond promptly to your inquiry.
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